ArticleBMJ open diabetes research & care2020
Association of visceral adiposity and clinical outcome among patients with aldosterone producing adenoma.
Article in BMJ open diabetes research & care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Clinical and biochemical outcomes after adrenalectomy for primary aldosteronism in tertiary and quaternary referral centers: data from SOPRANO study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Pooled it
- The differences of serum lipid profiles between primary aldosteronism and essential hypertension: a meta-analysis and systematic review.BMC endocrine disorders · 2022Pooled it
- Adipose Composition Before and After Primary Aldosteronism Treatment Depends on Primary Aldosteronism Subtypes and Plasma Aldosterone Concentration Before the Treatment.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Unilateral Primary Aldosteronism Lacking KCNJ5 Somatic Mutations Is Associated With an Elevated Risk of New-Onset Diabetes.Diabetes · 2025Article
- Myosteatosis and sarcopenia are linked to autonomous cortisol secretion in patients with aldosterone-producing adenomas.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Association of Aldosterone, Renin, and Aldosterone to Renin Ratio with Metabolic Profile in Primary Aldosteronism.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Adrenalectomy for primary aldosteronism and its related surgical characteristics.Frontiers in endocrinology · 2024Review
- Fat mass as an important predictor of persistent hypertension in patients with primary aldosteronism after adrenalectomy.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Cardiovascular and metabolic characters ofFrontiers in endocrinology · 2023Review
- Association of the ratio of visceral-to-subcutaneous fat volume with renal function among patients with primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Cerebro-Cardiovascular Risk, Target Organ Damage, and Treatment Outcomes in Primary Aldosteronism.Frontiers in cardiovascular medicine · 2021Review
- Evaluation of Abdominal Computed Tomography Scans for Differentiating the Discrepancies in Abdominal Adipose Tissue Between Two Major Subtypes of Primary Aldosteronism.Frontiers in endocrinology · 2021Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPrimary aldosteronism (PA) is a common form of secondary hypertension that has significant cardiovascular events and increased prevalence of metabolic syndrome and diabetics. Although plasma aldosterone concentration is positively correlated with visceral fat area (VFA) in non-PA individuals, the role of visceral adiposity associated with clinical success after surgery is not known. RESEARCH DESIGN AND
methodsWe analyzed patients who underwent adrenalectomy for aldosterone-producing adenoma (APA) at the Taiwan PA Investigator group. VFA was calculated from the abdominal CT scan at APA diagnosis, and all patients received adrenalectomy.
resultsThe study involved 100 consecutive patients with APA (42 males; mean age 49.3 years) matched with 41 essential hypertension (EH) patients. Patients with APA had smaller VFA (p=0.010) than their EH counterparts. Multiple linear regression analysis revealed that the duration of hypertension (p=0.007), but not plasma aldosterone, was negatively correlated with VFA in patients with APA. Logistic regression analysis showed that log VFA (OR=0.065, p
conclusionsPatients with APA had smaller VFA than their EH counterparts, and VFA increased after adrenalectomy. Clinical complete cure of hypertension after surgery was associated with smaller VFA and shorter duration of hypertension at PA diagnosis, suggesting a potential interplay of visceral adiposity and aldosterone of the patients with APA.
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