Evidence map›Paper›PMID 32713682›Full record

ReviewVaccine2020

Preventing infectious diseases for healthy ageing: The VITAL public-private partnership project.

Debbie Van Baarle, Kaatje Bollaerts, Giuseppe Del Giudice, Stephen Lockhart, Christine Luxemburger, Maarten J Postma, Aura Timen, Baudouin Standaert, Vaccines, Infectious Diseases in the Ageing Population (VITAL) consortium

Open access · hybridAbstract readReview
In one paragraph

Review in Vaccine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  3. Influenza vaccine-specific CD4NPJ vaccines · 2026
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  15. Reply to Anglemyer et al.The Journal of infectious diseases · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Debbie Van BaarleCenter for Infectious Disease Prevention, National Institute for Public Health and the Environment, Bilthoven, the Netherlands; Center for Translational Immunology, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands. Electronic address: debbie.van.baarle@rivm.nl.
Kaatje BollaertsP-95, Heverlee, Belgium.
Giuseppe Del GiudiceGSK, Siena, Italy.
Stephen LockhartPfizer, Hurley, United Kingdom.
Christine LuxemburgerSanofi Pasteur, Lyon, France.
Maarten J PostmaRijksuniversiteit Groningen, the Netherlands.
Aura TimenCenter for Infectious Disease Prevention, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Baudouin StandaertGSK, Wavre, Belgium.
Vaccines, Infectious Diseases in the Ageing Population (VITAL) consortium
GlaxoSmithKline (Belgium) · BENational Institute for Public Health and the Environment · NLPfizer (United Kingdom) · GBRijksmuseum · NLSanofi (France) · FRUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prevention of infectious diseases through immunisation of the growing ageing adult population is essential to improve healthy ageing. However, many licenced and recommended vaccines for this age group show signs of waning of the protective effect due to declining immune responses (immuno-senescence) and decreasing vaccine uptake. Today's major challenge is to improve vaccine effectiveness and uptake and to deploy efficient vaccination strategies for this age group. The Vaccines and InfecTious diseases in the Ageing popuLation (VITAL) project, with partners from 17 academic & research groups and public institutes as well as seven industry collaborators, aims to address this challenge. The ambition is to provide evidence-based knowledge to local decision makers. Using a holistic and multidisciplinary approach and novel analytical methods, VITAL will provide tools that allow the development of targeted immunisation programs for ageing adults in European countries. The project is based on four pillars focussing on the assessment of the burden of vaccine-preventable diseases in ageing adults, the dissection of the mechanisms underlying immuno-senescence, the analysis of the clinical and economic public health impact of vaccination strategies and the development of educational resources for healthcare professionals. By the end of the project, a clear, detailed, and integrated program should be available for implementing a consistent, affordable, and sustainable vaccination strategy for ageing adults with regular evaluations of its impact over time.

Indexed as

Communicable DiseasesHealthy AgingVaccinesAdultEuropeHumansPublic-Private Sector PartnershipsVaccinationVaccinesElderlyImmuno-senescenceInfectious diseasesPublic healthPublic-private partnershipVaccine

Identifiers

PMID32713682
PMCPMC7378501
OpenAlexW3044177891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.