Evidence map›Paper›PMID 32713291›Full record

ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2021

Multiple Motor Learning Processes in Humans: Defining Their Neurophysiological Bases.

Danny Spampinato, Pablo Celnik

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06137456 (First Report of a New Exoskeleton in Incomplete Spinal Cord Injury), which is not on this map. Cited by 75 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 3 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06137456 nacompletednot on this mapstarted 2022, after this paper: background citation

First Report of a New Exoskeleton in Incomplete Spinal Cord Injury: FreeGait®

TypeinterventionalSponsorAnkara City Hospital BilkentRan2022 to 2023Enrolled14ConditionsSpinal Cord Injuries, Walking, DifficultyArmsExoskeletal robotic therapy for walking., Conventional exercise therapy
3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 3 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
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  12. Network-oriented neurorehabilitation after stroke: a paradigmatic approach.Journal of neuroengineering and rehabilitation · 2026
    Review
  13. Article
  14. Review
  15. Article
  16. Eccentric Exercise and Muscle Damage: An Introductory Guide.Journal of functional morphology and kinesiology · 2026
    Review
  17. Article
  18. Article
  19. Review
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Danny SpampinatoUniversity College London, London, UK.ORCID 0000-0001-8471-0859
Pablo CelnikJohns Hopkins University, Baltimore, MD, USA.
Johns Hopkins University · USUniversity College London · GB

Funding

Novel Strategies to Enhance Motor Function After StrokeR01HD053793 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CELNIK, PABLO ARIEL · 2007 to 2019
$5.2M
Understanding Motor Behavior After StrokeR01HD073147 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CELNIK, PABLO ARIEL · 2012 to 2016
$1.7M
NICHD NIH HHS R01 HD053793NICHD NIH HHS R01 HD073147
6 · The paper itself

Abstract

Learning new motor behaviors or adjusting previously learned actions to account for dynamic changes in our environment requires the operation of multiple distinct motor learning processes, which rely on different neuronal substrates. For instance, humans are capable of acquiring new motor patterns via the formation of internal model representations of the movement dynamics and through positive reinforcement. In this review, we will discuss how changes in human physiological markers, assessed with noninvasive brain stimulation techniques from distinct brain regions, can be utilized to provide insights toward the distinct learning processes underlying motor learning. We will summarize the findings from several behavioral and neurophysiological studies that have made efforts to understand how distinct processes contribute to and interact when learning new motor behaviors. In particular, we will extensively review two types of behavioral processes described in human sensorimotor learning: (1) a recalibration process of a previously learned movement and (2) acquiring an entirely new motor control policy, such as learning to play an instrument. The selected studies will demonstrate in-detail how distinct physiological mechanisms contributions change depending on the time course of learning and the type of behaviors being learned.

Indexed as

Motor CortexBrainHumansLearningMotor SkillsMovementbrain stimulationmotor learningphysiologyskill learningTMS

Identifiers

PMID32713291
PMCPMC8151555
OpenAlexW3045171465

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.