ArticleAutophagy2020
Chloroquine in fighting COVID-19: good, bad, or both?
Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Designing a molecularly imprinted polymer-based electrochemical sensor for the sensitive and selective detection of the antimalarial chloroquine phosphate.Mikrochimica acta · 2024Article
- MERS-CoV nsp1 regulates autophagic flux via mTOR signalling and dysfunctional lysosomes.Emerging microbes & infections · 2022Article
- Review
- Safety considerations of chloroquine in the treatment of patients with diabetes and COVID-19.Chemico-biological interactions · 2022Article
- Friend or Foe? Implication of the autophagy-lysosome pathway in SARS-CoV-2 infection and COVID-19.International journal of biological sciences · 2022Review
- Darunavir ethanolate: Repurposing an anti-HIV drug in COVID-19 treatment.European journal of medicinal chemistry reports · 2021Review
- One Year of Coronavirus Disease 2019 (COVID-19) in Brazil: A Political and Social Overview.Annals of global health · 2021Review
- Impact of Treatment Regimens on Antibody Response to the SARS-CoV-2 Coronavirus.Frontiers in immunology · 2021Article
- Article
- Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?Autophagy · 2020Article
- The hallmarks of COVID-19 disease.PLoS pathogens · 2020Review
- A cohort study of 676 patients indicates D-dimer is a critical risk factor for the mortality of COVID-19.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Coronavirus disease 2019 (COVID-19) has attracted worldwide attention due to its speed of progression and elevated mortality rate. Amid the rush to develop treatments, recent hopes have focused on the anti-malarial drug chloroquine or the derivative hydroxychloroquine. Here, we briefly discuss the evidence for the potential use of these drugs with regard to the current pandemic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.