Evidence map›Paper›PMID 32713230›Full record

ArticleAdipocyte2020

HuR expression in adipose tissue mediates energy expenditure and acute thermogenesis independent of UCP1 expression.

Sarah R Anthony, Adrienne Guarnieri, Lindsey Lanzillotta, Anamarie Gozdiff, Lisa C Green, Katherine O'Grady, Robert N Helsley, A Phillip Owens Iii, Michael Tranter

Open access · goldAbstract read
In one paragraph

Article in Adipocyte, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. HuR inhibition reduces post-ischemic cardiac remodeling by dampening myocyte-dependent inflammatory gene expression and the innate immune response.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. HuR brings the heat: linking adipose tissue to cardiac dysfunction.American journal of physiology. Heart and circulatory physiology · 2021
    Article
  12. Adipocyte-specific deletion of HuR induces spontaneous cardiac hypertrophy and fibrosis.American journal of physiology. Heart and circulatory physiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sarah R AnthonyDepartment of Internal Medicine, Division of Cardiovascular Health and Disease, University of Cincinnati College of Medicine , Cincinnati, OH, USA.ORCID 0000-0002-6230-8188
Adrienne GuarnieriDepartment of Internal Medicine, Division of Cardiovascular Health and Disease, University of Cincinnati College of Medicine , Cincinnati, OH, USA.
Lindsey LanzillottaDepartment of Internal Medicine, Division of Cardiovascular Health and Disease, University of Cincinnati College of Medicine , Cincinnati, OH, USA.ORCID 0000-0002-0950-9810
Anamarie GozdiffDepartment of Internal Medicine, Division of Cardiovascular Health and Disease, University of Cincinnati College of Medicine , Cincinnati, OH, USA.
Lisa C GreenDepartment of Internal Medicine, Division of Cardiovascular Health and Disease, University of Cincinnati College of Medicine , Cincinnati, OH, USA.
Katherine O'GradyDepartment of Internal Medicine, Division of Cardiovascular Health and Disease, University of Cincinnati College of Medicine , Cincinnati, OH, USA.
Robert N HelsleyDivision of Pediatrics, Department of Gastroenterology, Hepatology, and Nutrition, University of Kentucky College of Medicine and Kentucky Children's Hospital , Lexington, KY, USA.ORCID 0000-0001-5000-3187
A Phillip Owens IiiDepartment of Internal Medicine, Division of Cardiovascular Health and Disease, University of Cincinnati College of Medicine , Cincinnati, OH, USA.
Michael TranterDepartment of Internal Medicine, Division of Cardiovascular Health and Disease, University of Cincinnati College of Medicine , Cincinnati, OH, USA.ORCID 0000-0002-0609-3717
University of Cincinnati Medical Center · USUniversity of Kentucky · US

Funding

LIPID, LIPOPROTEIN, AND GLUCOSE METABOLISM COREU24DK059630 · NIDDK · UNIVERSITY OF CINCINNATI · PI TSO, PATRICK · 2001 to 2015
$12.9M
NIDDK NIH HHS U24 DK059630
6 · The paper itself

Abstract

The goal of this study was to define the functional role of adipocyte-specific expression of the RNA binding protein Human antigen R (HuR). Mice with an adipocyte-specific deletion of HuR (

Indexed as

Gene Expression RegulationAdipose TissueAnimalsBiomarkersELAV-Like Protein 1Energy MetabolismGene DeletionMaleMiceMice, KnockoutThermogenesisUncoupling Protein 1BiomarkersElavl1 protein, mouseELAV-Like Protein 1Ucp1 protein, mouseUncoupling Protein 1adipose tissuebrown fatcalcium transportgene expressionHuRthermogenesisUCP1

Identifiers

PMID32713230
PMCPMC7469577
OpenAlexW3045062758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.