Evidence map›Paper›PMID 32713093›Full record

ArticleProtein science : a publication of the Protein Society2020

Structure and function of the juxtamembrane GAF domain of potassium biosensor KdpD.

Shivesh Kumar, Richard E Gillilan, Dinesh A Yernool

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Protein science : a publication of the Protein Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Structure and function of the juxtamembrane GAF domain of potassium biosensor KdpD.Protein science : a publication of the Protein Society · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shivesh KumarDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA.ORCID 0000-0002-3414-4091
Richard E GillilanMacromolecular Diffraction Facility, Cornell High Energy Synchrotron Source (MacCHESS), Cornell University, Ithaca, New York, USA.
Dinesh A YernoolDepartment of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.

Funding

Training and OutreachP30GM124166 · NIGMS · CORNELL UNIVERSITY · PI RICHARD A. CERIONE · 2019 to 2026
$28.3M
NIGMS NIH HHS 1-P30-GM124166-01A1NIGMS NIH HHS P30 GM124166
6 · The paper itself

Abstract

KdpD/KdpE two-component signaling system regulates expression of a high affinity potassium transporter responsible for potassium homeostasis. The C-terminal module of KdpD consists of a GAF domain linked to a histidine kinase domain. Whereas certain GAF domains act as regulators by binding cyclic nucleotides, the role of the juxtamembrane GAF domain in KdpD is unknown. We report the high-resolution crystal structure of KdpD GAF domain (KdpD

Indexed as

Protein MultimerizationEscherichia coliEscherichia coli ProteinsProtein Conformation, beta-StrandProtein DomainsProtein KinasesEscherichia coli ProteinsKdpD protein, E coliProtein Kinaseseffector modulefour-helix bundleGAF domainjuxtamembrane adapterpotassium biosensorsensor histidine kinase

Identifiers

PMID32713093
PMCPMC7454560

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.