Evidence map›Paper›PMID 32712960›Full record

ArticleHeadache2020

Patients With Vestibular Migraine are More Likely to Have Occipital Headaches than those With Migraine Without Vestibular Symptoms.

Anne-Sophie Wattiez, Sarah A O'Shea, Patrick Ten Eyck, Levi P Sowers, Ana Recober, Andrew F Russo, Deema Fattal

Open access · greenAbstract read
In one paragraph

Article in Headache, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Focused Update on Migraine and Vertigo Comorbidity.Current pain and headache reports · 2024
    Review
  5. Article
  6. Vestibular Migraine.Current neurology and neuroscience reports · 2022
    Review
  7. [Osmophobia and vestibular migraine]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2022
    Article
  8. Update on diagnosis and differential diagnosis of vestibular migraine.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Review
  9. Involvement of the cerebellum in migraine.Frontiers in systems neuroscience · 2022
    Review
  10. Cerebro-Cerebellar Networks in Migraine Symptoms and Headache.Frontiers in pain research (Lausanne, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anne-Sophie WattiezDepartment of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.ORCID https://orcid.org/0000-0002-4392-2211
Sarah A O'SheaDepartment of Neurology, University of Iowa, Iowa City, IA, USA.
Patrick Ten EyckInstitute for Clinical and Translational Science, University of Iowa, Iowa City, IA, USA.
Levi P SowersCenter for the Prevention and Treatment of Visual Loss, Iowa VA Health Care System, Iowa City, IA, USA.
Ana RecoberDepartment of Neurology, University of Iowa, Iowa City, IA, USA.
Andrew F RussoDepartment of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.
Deema FattalDepartment of Neurology, University of Iowa, Iowa City, IA, USA.
University of Iowa · USIowa City VA Health Care System · US

Funding

Perivascular mechanisms of CGRP-induced migraine symptomsR01NS075599 · NINDS · UNIVERSITY OF IOWA · PI RUSSO, ANDREW F · 2011 to 2023
$5.0M
Early auditory and imbalance measures in a mouse model of Alzheimer's Disease-SupplementR01DC017261 · NIDCD · UNIVERSITY OF ROCHESTER · PI LUEBKE, ANNE E · 2018 to 2022
$2.2M
Photosensitivity as a preclinical assessment for treatment of post-traumatic headacheI01RX002101 · VA · IOWA CITY VA MEDICAL CENTER · PI PIEPER, ANDREW A, RUSSO, ANDREW F · 2016 to 2020
–
Identification and treatment of brain regions causing post-traumatic headacheIK2RX002010 · VA · IOWA CITY VA MEDICAL CENTER · PI SOWERS, LEVI P · 2016 to 2020
–
NIDCD NIH HHS R01 DC017261NINDS NIH HHS R01 DC017261NINDS NIH HHS R01 NS075599Rehabilitation Research and Development Service A-ORD 1IO1RX002101Rehabilitation Research and Development Service IK2 RX002010 012020RRD VA I01 RX002101RRD VA IK2 RX002010
6 · The paper itself

Abstract

objectiveTo determine whether patients with vestibular migraine are more likely to suffer from an occipital headache than patients with migraine without vestibular symptoms.

backgroundVestibular migraine is an underdiagnosed disorder in which migraine is associated with vestibular symptoms. Anatomical evidence and symptomatology hint at the involvement of brain structures in the posterior fossa (back of the head location). We hypothesized that vestibular migraine patients are more likely than migraineurs without vestibular symptoms to experience headaches located in the back of the head, that is, occipital headaches.

methodsA retrospective cross-sectional study was conducted at the University of Iowa Hospital and Clinics. Chart analysis of 169 patients was performed. The primary outcome was the location of the headache in vestibular migraine patients and migraineurs without vestibular symptoms. The secondary outcomes included the association of vestibular migraine with gender, age at onset of headache, age at onset of vestibular symptoms (such as vertigo, head motion-induced dizziness), aura, motion sickness, other associated symptoms, family history of headaches, and family history of motion sickness.

resultsIn vestibular migraine group, 45/103 (44%) had occipital location for their headaches vs 12/66 (18%) in migraine patients without vestibular symptoms, for an odd's ratio of 3.5 (95% CI = 1.7-7.2, P < .001). Additionally, the age at onset of headache was greater in the vestibular migraine group (28 ± 12 vs 18 ± 9 years, P < .001) and motion sickness was more common (41/98 (42%) in the vestibular migraine group, 1/64 (2%) in the migraine without vestibular symptoms group, P < .001).

conclusionsThis study suggests that patients with vestibular migraine are more likely to have occipital headaches than patients with migraine without vestibular symptoms. Our data support the initiation of a prospective study to determine whether a patient presenting with occipital headaches, with late onset of age of headache, and with a history of motion sickness is at an increased risk for the possible development of vestibular migraine.

Indexed as

AdultAge of OnsetCross-Sectional StudiesDizzinessFemaleHeadacheHumansMaleMigraine DisordersMotion SicknessRetrospective StudiesVertigoVestibular Diseasesdizzinessheadache locationmigraineoccipitalvertigovestibular migraine

Identifiers

PMID32712960
PMCPMC7771256
OpenAlexW3045379946

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.