Evidence map›Paper›PMID 32712930›Full record

ArticleWorld journal of microbiology & biotechnology2020

Structure-based functional fitness analyses of carbapenemase variants identified among pathogenic carbapenem-resistant Gram-negative bacteria.

Arijit Pal, Indrani Bhattacharyya, Anusri Tripathi

Abstract read
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In one paragraph

Article in World journal of microbiology & biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Arijit PalDepartment of Biochemistry and Medical Biotechnology, Calcutta School of Tropical Medicine, 108, C.R. Avenue, Kolkata, 700 073, India.
Indrani BhattacharyyaDepartment of Microbiology, Calcutta School of Tropical Medicine, 108, C.R. Avenue, Kolkata, 700 073, India.
Anusri TripathiDepartment of Biochemistry and Medical Biotechnology, Calcutta School of Tropical Medicine, 108, C.R. Avenue, Kolkata, 700 073, India. anusri.stm@gmail.com.ORCID http://orcid.org/0000-0002-8720-4342
Medical College and Hospital, Kolkata · INCalcutta National Medical College and Hospital · IN

Funding

Indian Council of Medical Research 3/1/3/WL/JRF-2011/HRD-129 (41937)
6 · The paper itself

Abstract

Carbapenemase-mediated carbapenem resistance is a major public health concerns worldwide. In the present study, prevalence of circulating carbapenemases was estimated among carbapenem-resistant clinical isolates using PCR and sequencing. Diameters of zone of inhibition (ZDs) were compared for imipenem, meropenem and ertapenem among single carbapenemase producing isolates. Structure-based functional fitness of those carbapenemases was predicted through several in silico analyses. Approximately, 63.76% isolates demonstrated carbapenem resistance, of which 39.13% harboured carbapenemases like bla

Indexed as

Anti-Bacterial AgentsBacteriaBacterial Proteinsbeta-LactamasesCarbapenemsDrug Resistance, BacterialGram-Negative BacteriaHumansImipenemMicrobial Sensitivity TestsMolecular Docking SimulationAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsImipenemBioinformaticsCarbapenemasesCarbapenem resistanceMolecular dockingProtein stabilitySelection pressure

Identifiers

PMID32712930
OpenAlexW3045040548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.