Evidence map›Paper›PMID 32712896›Full record

ArticleProbiotics and antimicrobial proteins2021

Compatibility, Cytotoxicity, and Gastrointestinal Tenacity of Bacteriocin-Producing Bacteria Selected for a Consortium Probiotic Formulation to Be Used in Livestock Feed.

Mégane Eveno, Patricia Savard, Yanath Belguesmia, Laurent Bazinet, Frédérique Gancel, Djamel Drider, Ismail Fliss

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mégane EvenoUMR Transfrontalière BioEcoAgro N° 1158, Univ. Lille, INRAE, Univ. Liège, UPJV, YNCREA, Univ. Artois, Univ. Littoral Côte d'Opale, ICV - Institut Charles Viollette, F-59000, Lille, France.
Patricia SavardInstitute of Nutrition and Functional Foods (INAF), Dairy Research Center (STELA), Department of Food Sciences, Pavillon Paul-Comtois, 2425, rue de l'Agriculture, Université Laval, Québec, G1V 0A6, Canada.
Yanath BelguesmiaUMR Transfrontalière BioEcoAgro N° 1158, Univ. Lille, INRAE, Univ. Liège, UPJV, YNCREA, Univ. Artois, Univ. Littoral Côte d'Opale, ICV - Institut Charles Viollette, F-59000, Lille, France.
Laurent BazinetInstitute of Nutrition and Functional Foods (INAF), Dairy Research Center (STELA), Department of Food Sciences, Pavillon Paul-Comtois, 2425, rue de l'Agriculture, Université Laval, Québec, G1V 0A6, Canada.
Frédérique GancelUMR Transfrontalière BioEcoAgro N° 1158, Univ. Lille, INRAE, Univ. Liège, UPJV, YNCREA, Univ. Artois, Univ. Littoral Côte d'Opale, ICV - Institut Charles Viollette, F-59000, Lille, France.
Djamel DriderUMR Transfrontalière BioEcoAgro N° 1158, Univ. Lille, INRAE, Univ. Liège, UPJV, YNCREA, Univ. Artois, Univ. Littoral Côte d'Opale, ICV - Institut Charles Viollette, F-59000, Lille, France. djamel.drider@univ-lille.fr.
Ismail FlissInstitute of Nutrition and Functional Foods (INAF), Dairy Research Center (STELA), Department of Food Sciences, Pavillon Paul-Comtois, 2425, rue de l'Agriculture, Université Laval, Québec, G1V 0A6, Canada.
Université Laval · CAInstitut Charles Viollette · FRÉcole Polytechnique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriocin-producing Escherichia coli ICVB442, E. coli ICVB443, Enterococcus faecalis ICVB497, E. faecalis ICVB501, and Pediococcus pentosaceus ICVB491 strains were examined for their pathogenic risks and compatibility and hence suitability as consortium probiotic bacteria. Except for E. coli ICVB442, all were inclined to form biofilm. All were gelatinase-negative, sensitive to most of the antibiotics tested and not cytotoxic to porcine intestinal epithelial cells (IPEC-1) when tested at a multiplicity of infection (MOI) of 1. P. pentosaceus ICVB491 stood apart by inhibiting the other four strains. Both E. coli strains and E. faecalis ICVB497 strain were β-hemolytic. Survival in the TIM-1 dynamic model of the human digestive system was 139% for the tested E. coli ICVB443 strain, 46% for P. pentosaceus ICVB491, and 32% for the preferred E. faecalis ICVB501 strain. These three potential probiotics, which are bacteriocin-producing strains, will be considered for simultaneous use as consortium with synergistic interactions in vivo on animal model.

Indexed as

LivestockMicrobial ConsortiaProbioticsAnimal FeedAnimalsBacteriocinsBiofilmsCell LineEnterococcus faecalisEscherichia coliHumansIntestinesPediococcus pentosaceusSwineBacteriocinsBacteriocinBiocompatibilityGut microbiotaProbioticTIM-1

Identifiers

PMID32712896
OpenAlexW3044545125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.