ArticleGenes & genomics2020
Differential manifestation of ocular phenotypes in TALEN-mediated p19
Jin-Sung Park, Joo-Il Kim, Hyun-Jin Lim, Soo-Kyung Ryu, Euna Kwon, Kang-Min Han, Ki-Taek Nam, Han-Woong Lee, Byeong-Cheol Kang
Abstract read
In one paragraphArticle in Genes & genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
9 authors at 3 institutions in 2 countries.
Jin-Sung ParkDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
Joo-Il KimDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
Hyun-Jin LimDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
Soo-Kyung RyuDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
Euna KwonDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
Kang-Min HanGraduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Ki-Taek NamCollege of Medicine Severance Biomedical Science Institute, Yonsei University, Seoul, Republic of Korea.
Han-Woong LeeDepartment of Biochemistry, Yonsei University, Seoul, Republic of Korea.
Byeong-Cheol KangDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea. bckang@snu.ac.kr.ORCID 0000-0002-9485-516X Seoul National University · KRSeoul National University Hospital · KRYonsei University · KR
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
backgroundp19 OBJECT: We carried out a study to investigate into the effect of genetic background on the manifestation of p19
methodsWe characterized the phenotypes of novel p19
resultsNinety-five percent of FVB/N-p19
conclusionOur findings demonstrated surprisingly variable manifestation of p19
Indexed as
AnimalsCyclin-Dependent Kinase Inhibitor p16EyeFemaleMaleMiceMice, Inbred C57BLMice, Inbred StrainsMice, KnockoutOcular Physiological PhenomenaPhenotypeTranscription Activator-Like Effector NucleasesTranscription Activator-Like EffectorsVision, OcularCdkn2a protein, mouseCyclin-Dependent Kinase Inhibitor p16Transcription Activator-Like Effector NucleasesTranscription Activator-Like EffectorsCataractGenetic backgroundMouse strainp19arfPhenotypic variability
Identifiers
PMID32712838
OpenAlexW3044687126
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