Evidence map›Paper›PMID 32712725›Full record

ReviewWorld journal of microbiology & biotechnology2020

Morphology engineering: a new strategy to construct microbial cell factories.

Kaiyue Huo, Fengjie Zhao, Fang Zhang, Ruihua Liu, Chao Yang

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Developing Quorum Sensing-Based Collaborative Dynamic Control System in Halomonas TD01.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. The Performance and Evolutionary Mechanism ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Fine-tuning the cell morphology ofBiotechnology notes (Amsterdam, Netherlands) · 2023
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaiyue HuoKey Laboratory of Molecular Microbiology and Technology for Ministry of Education, Nankai University, Tianjin, 300071, China.
Fengjie ZhaoKey Laboratory of Molecular Microbiology and Technology for Ministry of Education, Nankai University, Tianjin, 300071, China.
Fang ZhangKey Laboratory of Molecular Microbiology and Technology for Ministry of Education, Nankai University, Tianjin, 300071, China.
Ruihua LiuState Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, 300071, China. yangyangliu@nankai.edu.cn.
Chao YangKey Laboratory of Molecular Microbiology and Technology for Ministry of Education, Nankai University, Tianjin, 300071, China. yangc20119@nankai.edu.cn.ORCID http://orcid.org/0000-0002-7607-6621

Funding

Natural Science Foundation of Tianjin 18JCYBJC24500the National Key Research and Development Program of China 2018YFA0900100the National Natural Science Funding of China 31670093
6 · The paper itself

Abstract

Currently, synthetic biology approaches have been developed for constructing microbial cell factories capable of efficient synthesis of high value-added products. Most studies have focused on the construction of novel biosynthetic pathways and their regulatory processes. Morphology engineering has recently been proposed as a novel strategy for constructing efficient microbial cell factories, which aims at controlling cell shape and cell division pattern by manipulating the cell morphology-related genes. Morphology engineering strategies have been exploited for improving bacterial growth rate, enlarging cell volume and simplifying downstream separation. This mini-review summarizes cell morphology-related proteins and their function, current advances in manipulation tools and strategies of morphology engineering, and practical applications of morphology engineering for enhanced production of intracellular product polyhydroxyalkanoate and extracellular products. Furthermore, current limitations and the future development direction using morphology engineering are proposed.

Indexed as

ActinsBacteriaBacterial ProteinsBiosynthetic PathwaysCell EngineeringCytoskeletal ProteinsCytoskeletonIndustrial MicrobiologySynthetic BiologyActinsBacterial ProteinsCytoskeletal ProteinsFtsZ protein, BacteriaCell morphology-related genesExtracellular productsMicrobial cell factoriesMorphology engineeringPolyhydroxyalkanoate

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.