ArticleEnvironmental monitoring and assessment2020
Heavy metal contamination in a highly consumed Brazilian fish: immunohistochemical and histopathological assessments.
Article in Environmental monitoring and assessment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Trace metals contamination in freshwater fish in Brazil: related factors, environmental impacts, and risks to human health.Environmental monitoring and assessment · 2026Pooled it
- Morphological and Histometric Alterations in Gonadal and Neural Tissues of Native and Non-Native Fishes From the Lower Doce River Basin in Southeastern Brazil.Anatomia, histologia, embryologia · 2026Article
- Article
- Differential gene expression and developmental pathologies associated with persistent organic pollutants in sentinel fish in Troutman Lake, Sivuqaq, Alaska.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Occupational risks associated with chronic kidney disease of non-traditional origin (CKDnt) in Brazil: it is time to dig deeper into a neglected problem.Jornal brasileiro de nefrologia · 2024Article
- Detecting Aquatic Pollution Using Histological Investigations of the Gills, Liver, Kidney, and Muscles ofToxics · 2022Article
- Morphological and Functional Alterations Induced by Two Ecologically Relevant Concentrations of Lead onInternational journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Due to industrial, rural, and domestic waste disposal, heavy metals such as cadmium (Cd), chromium (Cr), lead (Pb), zinc (Zn), copper (Cu), and iron (Fe) continually infiltrate aquatic environments. These pollutants do not degrade naturally and, thus, have a high capacity for bioaccumulation in tissues and organs. The present study uses histological and immunohistochemical analyses to evaluate the contamination status of Salminus franciscanus, a large and economically important fish. Levels of Cd, Cr, Pb, Zn, Cu, and Fe were evaluated by atomic absorption spectrometry in the liver and muscle of fish sampled from two tributaries of the upper São Francisco River Basin, Brazil: the Abaeté and Paraopeba Rivers. In addition, histopathological alterations and expressions of three environmental biomarkers were assessed: metallothionein (MT), heat shock protein-70 (HSP70), and cytochrome P450-1A (CYP1A). The results show that fish from the Paraopeba River are unsuitable for human consumption, with several metals being detected above the safe limits established by the World Health Organization. Histopathological alterations in the liver and spleen were also significantly more frequent in fish from the Paraopeba River than in those from the Abaeté River (P < 0.05). Significant differences in the expressions of environmental biomarkers were observed between the rivers. Fish from the Abaeté River presented significantly higher values of the gonadosomatic index (GSI) and lower levels of metal contamination in the liver and muscle.
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