Evidence map›Paper›PMID 32712534›Full record

ArticleNeurobiology of aging2020

Age-related changes in repetition suppression of neural activity during emotional future simulation.

Aleea L Devitt, Preston P Thakral, Karl Szpunar, Donna Rose Addis, Daniel L Schacter

Abstract read
In one paragraph

Article in Neurobiology of aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Emotional future simulations: neural and cognitive perspectives.Cerebral cortex (New York, N.Y. : 1991) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Evidence supporting a time-limited hippocampal role in retrieving autobiographical memories.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aleea L DevittDepartment of Psychology, Harvard University, Cambridge, MA, USA. Electronic address: aldevitt@gmail.com.
Preston P ThakralDepartment of Psychology, Harvard University, Cambridge, MA, USA.
Karl SzpunarDepartment of Psychology, Ryerson University, Toronto, ON, Canada.
Donna Rose AddisRotman Research Institute, Baycrest Health Sciences, Toronto, ON, Canada; Department of Psychology, University of Toronto, Toronto, ON, Canada; School of Psychology, The University of Auckland, Auckland, New Zealand.
Daniel L SchacterDepartment of Psychology, Harvard University, Cambridge, MA, USA.

Funding

Episodic Retrieval and Problem Solving in AgingR01AG008441 · NIA · UNIVERSITY OF ARIZONA · PI SCHACTER, DANIEL L · 1989 to 2022
$3.1M
NIA NIH HHS R01 AG008441
6 · The paper itself

Abstract

Despite advances in understanding the consequences of age-related episodic memory decline for future simulation, much remains unknown regarding changes in the neural underpinnings of future thinking with age. We used a repetition suppression paradigm to explore age-related changes in the neural correlates of emotional future simulation. Younger and older adults simulated positive, negative, and neutral future events either 2 or 5 times. Reductions in neural activity for events simulated 5 versus 2 times (i.e., repetition suppression) identify brain regions responsive to the specific emotion of simulated events. Critically, older adults showed greater repetition suppression than younger adults in the temporal pole for negative simulations, and the cuneus for positive simulations. These findings suggest that older adults distance themselves from negative future possibilities by thinking about them in a more semantic way, consistent with the view that older adults down-regulate negative affect and up-regulate positive affect. More broadly this study increases our understanding of the impact of aging on the neural underpinnings of episodic future simulation.

Indexed as

AdultAgedAge FactorsBrainCognitive AgingEmotionsFemaleHumansMaleMemory, EpisodicRepetition PrimingThinkingYoung AdultAgingEmotionEpisodic future thinking

Identifiers

PMID32712534
PMCPMC7484194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.