Evidence map›Paper›PMID 32711478›Full record

ArticleBMC microbiology2020

Whole genome sequencing of macrolide resistant Streptococcus pneumoniae serotype 19A sequence type 416.

Petra Spanelova, Vladislav Jakubu, Lucia Malisova, Martin Musilek, Jana Kozakova, Costas C Papagiannitsis, Ibrahim Bitar, Jaroslav Hrabak, Annalisa Pantosti, Maria Del Grosso and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. The Crisis of Macrolide Resistance in Pneumococci in Latin America.The American journal of tropical medicine and hygiene · 2024
    Review
  4. Article
  5. Epidemiology of non-vaccine serotypes ofHuman vaccines & immunotherapeutics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Petra SpanelovaCentre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic. petra.spanelova@szu.cz.ORCID 0000-0003-0688-6423
Vladislav JakubuCentre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic.
Lucia MalisovaCentre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic.
Martin MusilekCentre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic.
Jana KozakovaCentre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic.
Costas C PapagiannitsisFaculty of Medicine, Biomedical Center, Charles University, Plzen, Czech Republic.
Ibrahim BitarFaculty of Medicine, Biomedical Center, Charles University, Plzen, Czech Republic.
Jaroslav HrabakFaculty of Medicine, Biomedical Center, Charles University, Plzen, Czech Republic.
Annalisa PantostiDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Maria Del GrossoDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Helena ZemlickovaCentre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic.
Charles University · CZNational Institute of Public Health · CZIstituto Superiore di Sanità · ITNational Institute of Public Health · LA

Funding

Ministerstvo Zdravotnictví Ceské Republiky 16-27109A
6 · The paper itself

Abstract

backgroundThe resistance of Streptococcus pneumoniae to macrolides is becoming an increasingly important issue and thus it is important to understand the genetics related to adaptation of this species to the widespread use of antibiotics in Europe. The 58 isolates of S. pneumoniae belonging to sequence type (ST) 416 and serotype 19A and to several different phenotypes originated from Italy, Portugal and Czech Republic were thus sequenced on Illumina MiSeq. The aim of the study was to describe genetical origine of isolates, investigate their macrolide resistance and suggest reasons for spread of ST416 in the Czech Republic.

resultsInvestigation of genes associated with serotype determined serotype switch between 15B and 19A serotypes and core genome multilocus sequence typing (cgMLST) confirmed the origine of concerned isolates in Netherlands

conclusionsParticipation of 19A/ST416 on the spread of Netherlands

Indexed as

Drug Resistance, BacterialCzech RepublicGenome, BacterialHigh-Throughput Nucleotide SequencingHumansItalyMacrolidesMultilocus Sequence TypingNetherlandsPhylogenyPhylogeographyPneumococcal InfectionsPolymorphism, Single NucleotidePortugalSerogroupStreptococcus pneumoniaeMacrolides

Identifiers

PMID32711478
PMCPMC7382794
OpenAlexW3045308783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.