ArticleESC heart failure2020
Global longitudinal strain for prediction of ventricular arrhythmia in patients with heart failure.
Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Latin-American guidelines of recommendations at discharge from an acute coronary syndrome.Archivos de cardiologia de Mexico · 2024Guideline
- The effect of increased plasma potassium on myocardial function; a randomized POTCAST substudy.The international journal of cardiovascular imaging · 2023Trial
- Cardiac endogenous transmitter system: molecular features, functions, and clinical implications.European heart journal · 2026Review
- Risk stratification for sudden cardiac death in nonischemic dilated cardiomyopathy: a moving target?Frontiers in cardiovascular medicine · 2026Review
- Speckle tracking echocardiography for prediction of arrhythmias in idiopathic ventricular fibrillation.European heart journal. Imaging methods and practice · 2025Article
- Myocardial Performance Improvement After Iron Replacement in Heart Failure Patients: The IRON-PATH II Echo-Substudy.Journal of clinical medicine · 2025Article
- Cardiovascular imaging techniques for electrophysiologists.Nature cardiovascular research · 2025Review
- Effect of Global Longitudinal Strain at Discharge Period on Predicting Cardiac Defibrillator Implantation in STEMİ Patients with Impaired Left Ventricle Systolic Functions.Medicina (Kaunas, Lithuania) · 2025Article
- Predicting cardiovascular events in out-of-hospital patients presenting with atypical chest pain and complete left bundle branch block: role of CTA and echocardiographic Global Longitudinal Strain.Journal of geriatric cardiology : JGC · 2024Article
- Application of the Left Ventricular Pressure-Strain Loop Technique in Monitoring Improvement Factors of Patients With Heart Failure Reduced Ejection Fraction.Cardiovascular therapeutics · 2024Article
- Strain Imaging and Ventricular Arrhythmia.Diagnostics (Basel, Switzerland) · 2023Review
- Multimodality imaging in decompensated heart failure.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Longitudinal Speckle Tracking Strain Abnormalities in Chagas Disease: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- Direct left-ventricular global longitudinal strain (GLS) computation with a fully convolutional network.Journal of biomechanics · 2022Article
- Echocardiographic Advances in Dilated Cardiomyopathy.Journal of clinical medicine · 2021Review
- CMR-Based Risk Stratification of Sudden Cardiac Death and Use of Implantable Cardioverter-Defibrillator in Non-Ischemic Cardiomyopathy.International journal of molecular sciences · 2021Review
- Left Ventricular Deformation and Vortex Analysis in Heart Failure: From Ultrasound Technique to Current Clinical Application.Diagnostics (Basel, Switzerland) · 2021Review
- Global longitudinal strain for prediction of ventricular arrhythmia in patients with heart failure.ESC heart failure · 2020Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
aimsCurrently, the ejection fraction [left ventricular ejection fraction (LVEF)] is the main criterion used for implanting implantable cardioverter defibrillators (ICDs) for primary prevention. However, many of ICD receivers would not have an event and do not have any gains from the device. Consequently, improving the discrimination strategies is needed. Here, we aimed at assessing the role of global longitudinal strain (GLS) for such purpose. METHODS AND
resultsSeventy ischaemic or dilated cardiomyopathy cases characterized by LVEF ≤ 40% with a previously implanted ICD were enrolled. LVEF and GLS amounts were evaluated using 3D echocardiography. The occurrence of ventricular arrhythmias was checked by analysing the ICD history. Mean follow-up period of patients was 1.8 ± 0.6 years. There was a significant difference in the amount of GLS in arrhythmic cases compared with non-arrhythmic ones (-6.97 ± 3.06 vs -11.82 ± 4.25; P < 0.001). This difference was found in both ischaemic and dilated cardiomyopathy groups. A GLS below -10 cm/s could predict the occurrence of a ventricular event by 90% specificity and 72.2% sensitivity (area under the curve = 0.84, P < 0.001). While 27.39 (69.2%) patients with GLS below -10 cm/s had a ventricular event, only 3.31 (9.6%) of the patients with GLS above -10 had an event) P < 0.001). Those patients with a GLS ≥ 17 cm/s never experienced a ventricular arrhythmia.
conclusionsGlobal longitudinal strain is a more accurate predictor of ventricular arrhythmias in patients with reduced LVEF. Whether it may help in selecting more appropriate patients for ICD implantation or not should be evaluated within a randomized trial in the future.
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Registered trials
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