Evidence map›Paper›PMID 32710289›Full record

ArticleEuropean journal of epidemiology2020

Citrus intake and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC).

Yahya Mahamat-Saleh, Iris Cervenka, Marie Al-Rahmoun, Francesca R Mancini, Gianluca Severi, Reza Ghiasvand, Marit B Veierod, Saverio Caini, Domenico Palli, Edoardo Botteri and 28 more

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In one paragraph

Article in European journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Daily Lifestyle and Cutaneous Malignancies.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 20 institutions in 10 countries.

Yahya Mahamat-SalehCESP, Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris Saclay, 94 805, Villejuif, France.
Iris CervenkaCESP, Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris Saclay, 94 805, Villejuif, France.
Marie Al-RahmounCESP, Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris Saclay, 94 805, Villejuif, France.
Francesca R ManciniCESP, Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris Saclay, 94 805, Villejuif, France.
Gianluca SeveriCESP, Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris Saclay, 94 805, Villejuif, France.
Reza GhiasvandOslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Marit B VeierodOslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Saverio CainiCancer Risk Factors and Lifestyle Epidemiology Unit, Cancer Research, Prevention and Clinical Network Institute (ISPRO), Florence, Italy.
Domenico PalliCancer Risk Factors and Lifestyle Epidemiology Unit, Cancer Research, Prevention and Clinical Network Institute (ISPRO), Florence, Italy.
Edoardo BotteriDepartment of Bowel Cancer Screening, Cancer Registry of Norway, Oslo University Hospital, Oslo, Norway.
Carlotta SacerdotePiedmont Reference Centre for Epidemiology and Cancer Prevention (CPO Piemonte), Turin, 10126, Italy.
Fulvio RicceriEpidemiology Unit, ASL TO3, Piedmont Region, Grugliasco, 10095, Italy.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Eleni PeppaHellenic Health Foundation, Athens, Greece.
Carlo La VecchiaHellenic Health Foundation, Athens, Greece.
Kim OvervadDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Christina C DahmDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Anja OlsenDanish Cancer Society Research Center, Copenhagen, Denmark.
Anne TjønnelandDanish Cancer Society Research Center, Copenhagen, Denmark.
Aurora Perez-CornagoCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Paula JakszynUnit of Nutrition and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, ĹHospitallet de Llobregat, Barcelona, Spain.
Sara GrioniEpidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Matthias B SchulzeDepartment of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Guri SkeieDepartment of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.
Cristina LasherasDepartment of Functional Biology, University of Oviedo, Asturias, Spain.
Sandra Colorado-YoharDepartment of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain.
Miguel Rodríguez-BarrancoCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Tilman KühnDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Verena A KatzkeDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Pilar AmianoCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Rosario TuminoCancer Registry and Histopathology Department, Civic-M. P. Arezzo Hospital, ASP Ragusa, Ragusa, Italy.
Salvatore PanicoDipartimento di Medicina Clinica e Sperimentale, Federico II University, Naples, Italy.
Ana EzpondaClínica Universidad de Navarra, Pamplona, Spain.
Emily SonestedtNutritional Epidemiology, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Augustin ScalbertBiomarkers Group, International Agency for Research on Cancer, Lyon, France.
Elisabete WeiderpassInternational Agency for Research on Cancer, World Health Organization, Lyon, France.
Marie-Christine Boutron-RuaultCESP, Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris Saclay, 94 805, Villejuif, France.
Marina KvaskoffCESP, Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris Saclay, 94 805, Villejuif, France. Marina.KVASKOFF@gustaveroussy.fr.
Inserm · FRPiedmont Reference Center for Epidemiology and Cancer Prevention · ITCentre International de Recherche sur le Cancer · FRCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESHeidelberg University · DEHellenic Health Foundation · GRInstitut Gustave Roussy · FRUniversity of Oslo · NOAalborg University Hospital · DKAarhus University · DKCancer Registry of Norway · NOClinica Universidad de Navarra · ESDanish Cancer Society · DKFondazione IRCCS Istituto Nazionale dei Tumori · ITGerman Institute of Human Nutrition · DELund University · SERegione PiemonteUiT The Arctic University of Norway · NOUniversidad de Granada · ESUniversidad de Oviedo · ES

Funding

Cancer Research UK 14136 to EPIC-NorfolkCancer Research UK C570/A16491Cancer Research UK C8221/A19170 for EPIC-OxfordMedical Research Council 1000143 to EPIC-Norfolk, MR/M012190/1 to EPIC-OxfordMedical Research Council MR/M012190/1World Health Organization 001
6 · The paper itself

Abstract

Citrus intake has been suggested to increase the risk of skin cancer. Although this relation is highly plausible biologically, epidemiologic evidence is lacking. We aimed to examine the potential association between citrus intake and skin cancer risk. EPIC is an ongoing multi-center prospective cohort initiated in 1992 and involving ~ 520,000 participants who have been followed-up in 23 centers from 10 European countries. Dietary data were collected at baseline using validated country-specific dietary questionnaires. We used Cox proportional hazards regression models to compute hazard ratios (HR) and 95% confidence intervals (CI). During a mean follow-up of 13.7 years, 8448 skin cancer cases were identified among 270,112 participants. We observed a positive linear dose-response relationship between total citrus intake and skin cancer risk (HR = 1.10, 95% CI 1.03-1.18 in the highest vs. lowest quartile; P

Indexed as

CitrusAdultAgedCohort StudiesEuropeFemaleHumansKeratinocytesMaleMelanomaMiddle AgedNutritional StatusRisk AssessmentSkin NeoplasmsCitrusCohort studiesCutaneous melanomaEpidemiologyKeratinocyte cancers

Identifiers

PMID32710289
OpenAlexW3044681901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.