ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
A prospective nutritional assessment using Mini Nutritional Assessment-short form among patients with head and neck cancer receiving concurrent chemoradiotherapy.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Outcomes and other characteristics of the nutritional screening and assessment tools validation processes in hospitalized adults: a systematic review.Einstein (Sao Paulo, Brazil) · 2026Pooled it
- Malnutrition and radiation therapy in head and neck cancers, a systematic review on reported definitions and associated factors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Multidisciplinary Team Support for Patients With Head and Neck Cancer Receiving Radiotherapy: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Timing matters: gastrostomy placement and outcomes in patients with head and neck cancer undergoing chemoradiotherapy.Frontiers in nutrition · 2026Article
- The prognostic value of combining MNA-SF nutritional status and probable sarcopenia for 90-day readmission in elderly inpatients with multimorbidity.Frontiers in medicine · 2026Article
- Nephrotoxicity in locally advanced head and neck cancer: when the end justifies the means to preserve nutritional status during chemoradiation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Prospective study on health-related quality of life, oral mucositis and oral health on during treatment of head and neck cancer.BMC oral health · 2024Article
- The impact of nutritional intervention on quality of life and outcomes in patients with head and neck cancers undergoing chemoradiation.Frontiers in oncology · 2024Article
- Effect of prophylactic tube feeding in head and neck cancer patients with high Mallampati score undergoing definitive concurrent chemoradiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Effect of radiotherapy interruption on nasopharyngeal cancer.Frontiers in oncology · 2023Review
- Review
- The efficacy of immunonutrition in improving tolerance to chemoradiotherapy in patients with head and neck cancer, receiving nutritional counseling: study protocol of a randomized, open-label, parallel group, bicentric pilot study.Therapeutic advances in medical oncology · 2021Article
- Clinical Significance of Frailty on Treatment Outcome in Nongeriatric Patients With Head and Neck Cancer and Esophageal Cancer Undergoing Curative-Intent Concurrent Chemoradiotherapy.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo gold standard of nutritional assessment is established among patients with head and neck cancer (HNC) receiving concurrent chemoradiotherapy (CCRT). This study aimed to evaluate the clinical significance of pre-treatment nutritional status using the Mini Nutritional Assessment-short form (MNA-SF) among HNC patients receiving CCRT.
methodsA total of 461 consecutive patients with newly diagnosed HNC treated with definitive CCRT at three medical institutes were prospectively enrolled. Nutritional status was assessed using MNA-SF within 7 days before CCRT initiation. Patients were classified as having normal nutrition, at risk of malnutrition, and malnourished groups according to MNA-SF for comparison.
resultsThe 1-year overall survival rates were 89.8%, 76.8%, and 67.7% in the normal nutrition, at risk of malnutrition, and malnourished groups, respectively. Patients with normal nutrition had significantly lower rates of uncompleted radiotherapy and chemotherapy (4.5% and 4.1%, respectively) compared with patients at risk for malnutrition (14.1% and 11.5%, respectively) and those malnourished (11.1% and 11.1%, respectively). Patients with normal nutrition had significantly lower treatment-related complication rates regarding emergency room visits, hospital admission, and need for tubal feeding than those with at risk of malnutrition and malnourished. Patients with normal nutrition had significantly fewer severe hematologic toxicities (p = 0.044) and severe non-hematologic toxicities (p = 0.012) of CCRT than those malnourished.
conclusionPre-CCRT nutritional status identifies HNC patients vulnerable to treatment interruption and treatment complications. We suggest that nutritional assessment with MNA-SF should be incorporated in pre-CCRT evaluation for all HNC patients.
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