Evidence map›Paper›PMID 32710152›Full record

ReviewJournal of neural transmission (Vienna, Austria : 1996)2020

Effects of intrathecal baclofen therapy in subjects with disorders of consciousness: a reappraisal.

Raffaele Nardone, Luca Sebastianelli, Francesco Brigo, Stefan Golaszewski, Eugen Trinka, Elke Pucks-Faes, Leopold Saltuari, Viviana Versace

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neural transmission (Vienna, Austria : 1996), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Restoring consciousness with pharmacologic therapy: Mechanisms, targets, and future directions.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Raffaele NardoneDepartment of Neurology, Hospital of Merano (SABES-ASDAA), Merano-Meran, Italy. raffaele.nardone@asbmeran-o.it.
Luca SebastianelliDepartment of Neurorehabilitation, Hospital of Vipiteno, Vipiteno, Italy.
Francesco BrigoDepartment of Neurology, Hospital of Merano (SABES-ASDAA), Merano-Meran, Italy.
Stefan GolaszewskiDepartment of Neurology, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.
Eugen TrinkaDepartment of Neurology, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.
Elke Pucks-FaesDepartment of Neurology, Hochzirl Hospital, Zirl, Austria.
Leopold SaltuariDepartment of Neurorehabilitation, Hospital of Vipiteno, Vipiteno, Italy.
Viviana VersaceDepartment of Neurology, Hospital of Merano (SABES-ASDAA), Merano-Meran, Italy.
Krankenhaus Meran · ITParacelsus Medical University · ATUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baclofen is a structural analogue of gamma-amino-butyric acid (GABA), which reduces spastic hypertonia of striated muscle due to a mechanism of GABA

Indexed as

BaclofenMuscle Relaxants, CentralConsciousnessgamma-Aminobutyric AcidHumansInjections, SpinalMuscle SpasticityBaclofengamma-Aminobutyric AcidMuscle Relaxants, CentralBaclofenDisorders of consciousnessGABABIntrathecal baclofen administration

Identifiers

PMID32710152
OpenAlexW3045458289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.