ArticleScientific reports2020
The association of chronic anxiousness with cardiovascular disease and mortality in the community: results from the Gutenberg Health Study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Candidate Biological Markers for Social Anxiety Disorder: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Mental Disorders as Risk Factors for New Onset Cardiovascular Diseases.Biomedicines · 2026Review
- Improvement of anxious but not depressive symptoms is associated with functional outcomes of psychocardiological rehabilitation.Scientific reports · 2025Article
- Does Mental Distress Predict Cardiac Surgical Outcome?The Thoracic and cardiovascular surgeon · 2025Article
- Enhanced Brain-Heart Connectivity as a Precursor of Reduced State Anxiety after Therapeutic Virtual Reality Immersion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Cortisol, cardiovascular risk, and anxiety in full-time workers in Cartagena, Colombia, 2023.Frontiers in psychiatry · 2025Article
- Anxiety, depression, working from home and health-related behaviours during COVID-19: Structural equation modelling and serial mediation of associations with angina, heart attacks and stroke.Journal of health psychology · 2024Article
- Chronic disease outcome metadata from German observational studies - public availability and FAIR principles.Scientific data · 2023Article
- Family history of stroke - a useful clue for the primary care physician and stroke neurologist: a narrative review.Postepy psychiatrii neurologii · 2023Review
- Hypertension, Anxiety and Obstructive Sleep Apnea in Cardiovascular Disease and COVID-19: Mediation by Dietary Salt.Diseases (Basel, Switzerland) · 2022Article
- Association between social phobia and the risk of arrhythmia using the Korean National Sample Cohort: a retrospective cohort study.BMC psychiatry · 2022Article
- Editorial: Psychocardiology then and now - the genesis of a discipline.Frontiers in psychiatry · 2022Article
- Article
- Demographic Differences in Insomnia and Anxiety and the Association with Cardiovascular Risk Factors among Jordanian Healthy Adult.Iranian journal of nursing and midwifery researchArticle
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a large German community sample of adults, we investigated the association of chronic anxiousness with cardiovascular disease and mortality. Self-reported anxiousness from 11,643 German adults between 40 and 80 years of age from the Gutenberg Health Study (GHS) was analyzed over 5 years. Multivariable regression modeling assessed the relation between the variables, cardiovascular disease and mortality. Twelve percent of the participants reported consistently raised (chronic) anxiousness over at least 2.5 years. Anxiousness was more often reported by female, younger participants with a lower socioeconomic status, smokers and those with a family history of stroke and myocardial infarction. New onset of cardiovascular disease was linked to chronic anxiousness in men and new onset of anxiousness in women. However, chronic anxiousness did not predict all-cause mortality. Our results revealed that anxiousness is highly prevalent in German adults from middle to old age, affecting women in particular. In our study, we found sex-specific associations between new onset of cardiovascular disease and different forms of anxiousness in men and women. We suggest that even subclinical levels of anxiety need to be considered as cardiovascular risk factors. To elucidate potential harm of anxiousness for mental and physical health, we propose sex-specific analyses in further research studies, taking age and the course of anxiousness into account.
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