Evidence map›Paper›PMID 32709749›Full record

ArticleThe Journal of biological chemistry2020

Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F.

Trieu Le, Son C Le, Yang Zhang, Pengfei Liang, Huanghe Yang

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Polymodal Control of TMEM16x Channels and Scramblases.International journal of molecular sciences · 2022
    Review
  7. Virus-Induced Membrane Fusion in Neurodegenerative Disorders.Frontiers in cellular and infection microbiology · 2022
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Trieu LeDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA.
Son C LeDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA.ORCID 0000-0002-7647-5307
Yang ZhangDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA.
Pengfei LiangDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA.
Huanghe YangDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA huanghe.yang@duke.edu.ORCID 0000-0001-9521-9328
Duke Medical Center · USDuke University · US

Funding

Manipulating TMEM16F lipid scramblase to understand the transbilayer phospholipid transport phenomenonDP2GM126898 · NIGMS · DUKE UNIVERSITY · PI YANG, HUANGHE · 2017 to 2017
$2.2M
NIGMS NIH HHS DP2 GM126898
6 · The paper itself

Abstract

TMEM16 Ca

Indexed as

AnimalsAnoctaminsCatechinEnzyme InhibitorsHEK293 CellsHumansMicePhospholipidsPhospholipid Transfer ProteinsPolyphenolsTanninsANO6 protein, mouseAnoctaminsCatechinEnzyme Inhibitorsepigallocatechin gallatePhospholipidsPhospholipid Transfer ProteinsPolyphenolsTanninsANO6CaPLSaseepigallocatechin gallate (EGCG)fluorescenceion channelion channelsmembrane lipidmembrane transportpharmacologyphospholipidphospholipid scramblasepolyphenolscramblasetannic acidTMEM16F

Identifiers

PMID32709749
PMCPMC7458812
OpenAlexW3044781958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.