Trial reportJournal of the American Society of Nephrology : JASN2020
Long-Term Functional Patency and Cost-Effectiveness of Arteriovenous Fistula Creation under Regional Anesthesia: a Randomized Controlled Trial.
Trial report in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01706354 (Does Regional Compared to Local Anaesthesia Influence Outcome After Arteriovenous Fistula Creation?), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Does Regional Compared to Local Anaesthesia Influence Outcome After Arteriovenous Fistula Creation?
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Summary of the best evidence for preventing the failure of autologous arteriovenous fistulas in maintenance hemodialysis patients.Frontiers in cardiovascular medicine · 2026Pooled it
- Regional vs. Local Anesthesia for Arteriovenous Fistula Creation in Adults With End-Stage Kidney Disease: A Grade Assessed Systematic Review and Meta-Analysis.Seminars in dialysisPooled it
- Effect of no-touch versus conventional technique on arteriovenous fistula outcomes: a randomised controlled trial.Journal of nephrology · 2024Trial
- Peri-Operative Surgical and Anaesthetic Predictors of Autogenous Arteriovenous Fistula (AVF) Maturation: A Retrospective Cohort Analysis.Vascular health and risk management · 2026Article
- Improvement of wound healing after diabetic foot debridement by a novel high ankle block: a randomized controlled trial.American journal of translational research · 2026Article
- Article
- Perioperative Management of the Patient Receiving Maintenance Hemodialysis.Anesthesiology · 2025Article
- O2C-Based Evaluation of Microperfusion During Dialysis Fistula Creation.Journal of clinical medicine · 2025Article
- Similar outcomes of arteriovenous fistulae created under general or regional anesthesia.The journal of vascular access · 2025Article
- Fibroblast growth factor 21 predicts arteriovenous fistula functional patency loss and mortality in patients undergoing maintenance hemodialysis.Renal failure · 2024Article
- Efficacy of brachial plexus block in reducing radial artery spasm during interventional aneurysm surgery.iScience · 2024Article
- Radiocephalic Arteriovenous Fistula Patency and Use: A Post Hoc Analysis of Multicenter Randomized Clinical Trials.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- Local anesthetics for the Nephrologist.Clinical kidney journal · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRegional anesthesia improves short-term blood flow through arteriovenous fistulas (AVFs). We previously demonstrated that, compared with local anesthesia, regional anesthesia improves primary AVF patency at 3 months.
methodsTo study the effects of regional versus local anesthesia on longer-term AVF patency, we performed an observer-blinded randomized controlled trial at three university hospitals in Glasgow, United Kingdom. We randomly assigned 126 patients undergoing primary radiocephalic or brachiocephalic AVF creation to receive regional anesthesia (brachial plexus block; 0.5% L-bupivacaine and 1.5% lidocaine with epinephrine) or local anesthesia (0.5% L-bupivacaine and 1% lidocaine). This report includes findings on primary, functional, and secondary patency at 12 months; reinterventions; and additional access procedures (primary outcome measures were previously reported). We analyzed data by intention to treat, and also performed cost-effectiveness analyses.
resultsAt 12 months, we found higher primary patency among patients receiving regional versus local anesthesia (50 of 63 [79%] versus 37 of 63 [59%] patients; odds ratio [OR], 2.7; 95% confidence interval [95% CI], 1.6 to 3.8;
conclusionsCompared with local anesthesia, regional anesthesia significantly improved both primary and functional AVF patency at 1 year and is cost-effective. CLINICAL TRIAL REGISTRY NAME AND REGISTRATION NUMBER: Local Anaesthesia versus Regional Block for Arteriovenous Fistulae, NCT01706354.
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