Evidence map›Paper›PMID 32709690›Full record

ReviewDevelopment (Cambridge, England)2020

Cell death in animal development.

Piya Ghose, Shai Shaham

Open access · bronzeAbstract readReview
In one paragraph

Review in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Matters of life and death in computational cell biology.NPJ systems biology and applications · 2026
    Review
  5. bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Zebrafish crocc2 mutants exhibit divergent craniofacial shape, misregulated variability, and aberrant cartilage morphogenesis.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Exposure to low-dose cadmium induces testicular ferroptosis.Ecotoxicology and environmental safety · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Piya GhoseDepartment of Biology, The University of Texas at Arlington, 655 Mitchell St., Arlington, TX 76019, USA piya.ghose@uta.edu shaham@rockefeller.edu.ORCID 0000-0001-5612-617X
Shai ShahamLaboratory of Developmental Genetics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA piya.ghose@uta.edu shaham@rockefeller.edu.ORCID 0000-0002-3751-975X
Rockefeller University · USThe University of Texas at Arlington · US

Funding

Glial Control of Neuron Development and Function - Administrative SupplementR35NS105094 · NINDS · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2018 to 2025
$8.9M
NINDS NIH HHS R35 NS105094
6 · The paper itself

Abstract

Cell death is an important facet of animal development. In some developing tissues, death is the ultimate fate of over 80% of generated cells. Although recent studies have delineated a bewildering number of cell death mechanisms, most have only been observed in pathological contexts, and only a small number drive normal development. This Primer outlines the important roles, different types and molecular players regulating developmental cell death, and discusses recent findings with which the field currently grapples. We also clarify terminology, to distinguish between developmental cell death mechanisms, for which there is evidence for evolutionary selection, and cell death that follows genetic, chemical or physical injury. Finally, we suggest how advances in understanding developmental cell death may provide insights into the molecular basis of developmental abnormalities and pathological cell death in disease.

Indexed as

Cell DeathAnimalsApoptosisApoptosomesAutophagyCaspasesGene Expression Regulation, DevelopmentalInvertebratesMammalsSignal TransductionApoptosomesCaspasesApoptosisCaspaseCell compartment eliminationCell deathLCDLinker cell-type deathNon-apoptotic cell deathPathological cell death

Identifiers

PMID32709690
PMCPMC7390631
OpenAlexW3044982446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.