Evidence map›Paper›PMID 32709424›Full record

ReviewThe Journal of allergy and clinical immunology2021

Flow cytometric identification of T

Jennifer S Chen, Jessica D S Grassmann, Uthaman Gowthaman, Sam J Olyha, Tregony Simoneau, M Cecilia Berin, Stephanie C Eisenbarth, Adam Williams

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. A single priming event prevents oral tolerance to peanut.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Anaphylaxis: Focus on Transcription Factor Activity.International journal of molecular sciences · 2021
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jennifer S ChenDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, Conn; Department of Immunobiology, Yale University School of Medicine, New Haven, Conn.
Jessica D S GrassmannJackson Laboratory for Genomic Medicine, Farmington, Conn.
Uthaman GowthamanDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, Conn; Department of Immunobiology, Yale University School of Medicine, New Haven, Conn.
Sam J OlyhaDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, Conn; Department of Immunobiology, Yale University School of Medicine, New Haven, Conn.
Tregony SimoneauDepartment of Pediatrics, Harvard Medical School, Boston, Mass; Division of Respiratory Diseases, Boston Children's Hospital, Boston, Mass.
M Cecilia BerinJaffe Food Allergy Institute/Immunology Institute, Icahn School of Medicine at Mount Sinai, New York.
Stephanie C EisenbarthDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, Conn; Department of Immunobiology, Yale University School of Medicine, New Haven, Conn.
Adam WilliamsJackson Laboratory for Genomic Medicine, Farmington, Conn; Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Conn. Electronic address: adam.williams@jax.org.
Yale University · USJackson Laboratory · USHarvard University · USIcahn School of Medicine at Mount Sinai · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
Immune Mechanisms Regulating AllergyR01AI136942 · NIAID · YALE UNIVERSITY · PI Stephanie Caroline Eisenbarth, ADAM WILLIAMS · 2018 to 2026
$5.1M
lncRNA Control of Airway Epithelial Cell Responses to Type 2 InflammationR01AI141609 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WILLIAMS, ADAM · 2019 to 2022
$2.4M
Novel tools to maximize profiling of tissue and antigen specific immune dysregulation in allergy and inflammatory bowel disesaseU24AI118644 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BERIN, CECILIA, MERAD, MIRIAM · 2015 to 2020
$2.4M
Regulation of adaptive immunity by the NOD-like receptor NLRP10R01AI108829 · NIAID · YALE UNIVERSITY · PI EISENBARTH, STEPHANIE CAROLINE · 2014 to 2018
$2.1M
The Role of the lncRNA MORRBID in Controlling Dendritic Cell Lifespan and Adaptive ImmunityR21AI135221 · NIAID · JACKSON LABORATORY · PI WILLIAMS, ADAM · 2018 to 2019
$520k
The Function of lncRNAs in Airway Epithelial CellsR21AI133440 · NIAID · JACKSON LABORATORY · PI WILLIAMS, ADAM · 2018 to 2019
$520k
The adaptive immune response to food antigens in the gutR56AI155497 · NIAID · YALE UNIVERSITY · PI EISENBARTH, STEPHANIE CAROLINE · 2021 to 2021
$448k
Regulation of T cell-derived cytokines in allergic airway inflammationF30HL149151 · NHLBI · YALE UNIVERSITY · PI CHEN, JENNIFER S · 2020 to 2022
$113k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS F30 HL149151NIAID NIH HHS R01 AI108829NIAID NIH HHS R01 AI136942NIAID NIH HHS R01 AI141609NIAID NIH HHS R21 AI133440NIAID NIH HHS R21 AI135221NIAID NIH HHS R56 AI155497NIAID NIH HHS U24 AI118644NIGMS NIH HHS T32 GM007205
6 · The paper itself

Abstract

Anaphylaxis is a life-threatening allergic reaction caused by cross-linking of high-affinity IgE antibodies on the surface of mast cells and basophils. Understanding the cellular mechanisms that lead to high-affinity IgE production is required to develop better therapeutics for preventing this severe reaction. A recently discovered population of T follicular helper T

Indexed as

T Follicular Helper CellsT-Lymphocyte SubsetsAnimalsCell SeparationFlow CytometryHumansMiceallergyIgEIL-13IL-4IL-5intracellular cytokine stainingT(fh)13 cellsT follicular helper cells

Identifiers

PMID32709424
PMCPMC7854882
OpenAlexW3044860556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.