ArticleFertility and sterility2020
Association between in vitro fertilization and ischemic placental disease by gestational age.
Article in Fertility and sterility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Prenatal alcohol exposure is associated with altered feto-placental blood flow and sex-specific placental changes.JCI insight · 2025Article
- Prevalence, risk factors, and adverse perinatal outcomes in Chinese women with preeclampsia: a large retrospective cohort study.Journal of health, population, and nutrition · 2025Article
- Risks of Placental Abruption and Preterm Delivery in Patients Undergoing Assisted Reproduction.JAMA network open · 2024Article
- An Exploration of Organoid Technology: Present Advancements, Applications, and Obstacles.Current pharmaceutical biotechnology · 2024Review
- Pregnancies through oocyte donation. A mini review of pathways involved in placental dysfunction.Frontiers in medicine · 2024Review
- Risk factors for stillbirth at term: an Italian area-based, prospective cohort study.AJOG global reports · 2023Article
- Pregnancy by Oocyte Donation: Reviewing Fetal-Maternal Risks and Complications.International journal of molecular sciences · 2023Review
- Cesarean Delivery Trends Among Patients at Low Risk for Cesarean Delivery in the US, 2000-2019.JAMA network open · 2023Article
- Pregnancy outcomes and risk factors for preeclampsia in dichorionic twin pregnancies after in vitro fertilization: a five-year retrospective study.BMC pregnancy and childbirth · 2022Observational
- Effects of Different Endometrial Preparation Regimens during IVF on Incidence of Ischemic Placental Disease for FET Cycles.Journal of clinical medicine · 2022Article
- Analysis of the risk of complications during pregnancy in pregnant women with assisted reproductive technology: a retrospective study using registry linkage from 2013 to 2018 in Shanghai, China.BMC pregnancy and childbirth · 2022Article
- Incidence of Infertility and Pregnancy Complications in US Female Surgeons.JAMA surgery · 2021Article
- The value of transvaginal 4-dimensional hysterosalpingo-contrast sonography in predicting the necessity of assisted reproductive technology for women with tubal factor infertility.Quantitative imaging in medicine and surgery · 2021Article
- The New Old CD8+ T Cells in the Immune Paradox of Pregnancy.Frontiers in immunology · 2021Review
- Integrated Analysis of Hub Genes and MicroRNAs in Human Placental Tissues fromFrontiers in endocrinology · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate the association between in vitro fertilization (IVF) and ischemic placental disease (IPD), stratified by gestational age.
designWe performed a secondary analysis of a retrospective cohort study of deliveries.
settingDeliveries were performed over 15 years at a single tertiary hospital. PATIENT(S): We included all parturients who had a live born infant or an intrauterine fetal demise (IUFD). INTERVENTION(S): We compared pregnancies resulting from IVF cycles to non-IVF pregnancies. MAIN OUTCOME MEASURE(S): The primary outcomes were preterm and term IPD (preeclampsia, placental abruption, small-for-gestational age infant [SGA], or an intrauterine fetal demise [IUFD] due to placental insufficiency). RESULT(S): Of the 69,084 deliveries during the study period, 3,763 (5.4%) were conceived with IVF. The incidence of preterm delivery was 32.6% in IVF pregnancies and 10.8% in non-IVF pregnancies. Multiple gestations were more common in IVF pregnancies. Compared to non-IVF pregnancies, IVF pregnancies were more likely to develop both preterm and term IPD, even after adjustment for maternal age and parity. The risk of preterm IPD was 4 times higher (95% confidence interval, 3.7-4.4) in patients who underwent IVF compared with those who did not undergo IVF. Among parturients who delivered at ≥37 weeks of gestation, IVF pregnancies had 1.7 times the risk of term IPD (95% confidence interval, 1.6-1.9) compared with non-IVF pregnancies. CONCLUSION(S): IVF was strongly associated with preterm IPD. We found a similar, but attenuated, association between IVF and term IPD. The stronger association with preterm IPD suggests an association between IVF and placental insufficiency.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.