Evidence map›Paper›PMID 32709165›Full record

ArticleBiomedicines2020

Pharmacological Effects of a Novel Bradykinin-Related Peptide (RR-18) from the Skin Secretion of the Hejiang Frog (

Xiaowei Zhou, Jie Xu, Ruimin Zhong, Chengbang Ma, Mei Zhou, Zhijian Cao, Xinping Xi, Chris Shaw, Tianbao Chen, Lei Wang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Animal Venoms-Curse or Cure?Biomedicines · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Xiaowei ZhouInstitute of Translational Medicine, Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau.
Jie XuNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, UK.
Ruimin ZhongDepartment of Nutrition, Henry Fok School of Food Science and Engineering, Shaoguan University, Shaoguan 512005, China.
Chengbang MaNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, UK.
Mei ZhouNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, UK.ORCID 0000-0003-2576-0252
Zhijian CaoState Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan 430072, China.
Xinping XiNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, UK.
Chris ShawNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, UK.
Tianbao ChenNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, UK.ORCID 0000-0001-8011-9260
Lei WangNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, UK.ORCID 0000-0002-8811-8489
Hang Fai KwokInstitute of Translational Medicine, Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau.ORCID 0000-0002-6349-4517
Queen's University Belfast · GBShaoguan University · CNUniversity of Macau · MOWuhan University · CN

Funding

Fundo para o Desenvolvimento das Ciências e da Tecnologia 019/2017/A1Youth Innovative Talents Project of Education Department of Guangdong Province 2019KQNCX140
6 · The paper itself

Abstract

Bradykinin (BK) and bradykinin-related peptides (BRPs), which were identified from a diversity of amphibian skin secretions, exerted contractile and relaxing effects on non-vascular and vascular smooth muscle, respectively. Here, we report a novel bradykinin-related peptide with a molecular mass of 1890.2 Da, RVAGPDKPARISGLSPLR, which was isolated and identified from

Indexed as

antagonistbradykinin related peptidefrogskin secretionsmooth muscle

Identifiers

PMID32709165
PMCPMC7400415
OpenAlexW3043275395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.