Evidence map›Paper›PMID 32709127›Full record

ArticleInternational journal of molecular sciences2020

Inter-Regulation of K

Jérôme Clatot, Nathalie Neyroud, Robert Cox, Charlotte Souil, Jing Huang, Pascale Guicheney, Charles Antzelevitch

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. MOG1medRxiv : the preprint server for health sciences · 2025
    Article
  3. Review
  4. Article
  5. Requirement of β subunit for the reduced voltage-gated NaThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  6. Biophysical mechanisms of myocardium sodium channelopathies.Pflugers Archiv : European journal of physiology · 2024
    Review
  7. Review
  8. Article
  9. KCells · 2023
    Review
  10. J wave syndromes: What's new?Trends in cardiovascular medicine · 2022
    Review
  11. Review
  12. Review
  13. Article
  14. Pharmacological Approaches for the Modulation of the Potassium Channel KInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Jérôme ClatotDepartment of Cardiovascular Research, Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA.ORCID 0000-0003-2896-3469
Nathalie NeyroudTeam "Genomics and Pathophysiology of Myocardial Diseases", Faculté de Médecine Pitié-Salpêtrière, 91 Boulevard de l'Hôpital, Sorbonne Université, UMR_S1166, F-75013 Paris, France.ORCID 0000-0003-3382-7680
Robert CoxDepartment of Cardiovascular Research, Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA.
Charlotte SouilTeam "Genomics and Pathophysiology of Myocardial Diseases", Faculté de Médecine Pitié-Salpêtrière, 91 Boulevard de l'Hôpital, Sorbonne Université, UMR_S1166, F-75013 Paris, France.
Jing HuangDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Pascale GuicheneyTeam "Genomics and Pathophysiology of Myocardial Diseases", Faculté de Médecine Pitié-Salpêtrière, 91 Boulevard de l'Hôpital, Sorbonne Université, UMR_S1166, F-75013 Paris, France.ORCID 0000-0002-7663-2050
Charles AntzelevitchDepartment of Cardiovascular Research, Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA.ORCID 0000-0001-7349-1582
Inserm · FRChildren's Hospital of Philadelphia · USLankenau Institute for Medical Research · USMain Line Health · USUniversity of Pennsylvania · US

Funding

Development of a whole heart model of the J wave syndromes and novel approaches to pharmacologic management of associated life-threatening arrhythmiasR01HL152201 · NHLBI · LANKENAU INSTITUTE FOR MEDICAL RESEARCH · PI ANTZELEVITCH, CHARLES, DI DIEGO, JOSE M. · 2020 to 2023
$2.5M
NHLBI NIH HHS R01 HL152201
6 · The paper itself

Abstract

backgroundGenetic variants in voltage-gated sodium channels (Na

methodsBicistronic and other constructs were used to express WT or variant Na

results

conclusionNa

Indexed as

Brugada SyndromeChannelopathiesGenetic VariationHEK293 CellsHumansNAV1.1 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelPoint MutationShal Potassium ChannelsSpinocerebellar AtaxiasVoltage-Gated Sodium ChannelsKCND3 protein, humanNAV1.1 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelSCN1A protein, humanSCN5A protein, humanShal Potassium ChannelsVoltage-Gated Sodium ChannelsarrhythmiaBrugada syndromechannelopathiesKCND3Kv4.3Nav1.1Nav1.5SCN1ASCN5Aspinocerebellar ataxia

Identifiers

PMID32709127
PMCPMC7404392
OpenAlexW3042588125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.