Evidence map›Paper›PMID 32709050›Full record

ReviewInternational journal of molecular sciences2020

Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products.

Dongchen An, Steve Peigneur, Louise Antonia Hendrickx, Jan Tytgat

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 1 pooled it
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 1 synthesis or guideline pooled it, 194 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Review
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  7. Review
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  9. Review
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  12. Synthesis of Novel Chloro-Benzo [Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  13. Benzo[International journal of molecular sciences · 2025
    Article
  14. Article
  15. Review
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  20. Chemical Profiling of Polyphenolic Fraction ofPlants (Basel, Switzerland) · 2025
    Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dongchen AnToxicology and Pharmacology, KU Leuven, Campus Gasthuisberg, O&N 2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium.
Steve PeigneurToxicology and Pharmacology, KU Leuven, Campus Gasthuisberg, O&N 2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium.ORCID 0000-0003-0504-5702
Louise Antonia HendrickxToxicology and Pharmacology, KU Leuven, Campus Gasthuisberg, O&N 2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium.ORCID 0000-0002-9317-7862
Jan TytgatToxicology and Pharmacology, KU Leuven, Campus Gasthuisberg, O&N 2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium.
KU Leuven · BE

Funding

Catholic University of Leuven (KU Leuven) PDM/19/164China Scholarship Council Chinese Scholarship Councel - CSC - 201907060021FWO-Vlaanderen G0E7120N, GOC2319N and GOA4919N
6 · The paper itself

Abstract

Cannabinoid receptors (CB1 and CB2), as part of the endocannabinoid system, play a critical role in numerous human physiological and pathological conditions. Thus, considerable efforts have been made to develop ligands for CB1 and CB2, resulting in hundreds of phyto- and synthetic cannabinoids which have shown varying affinities relevant for the treatment of various diseases. However, only a few of these ligands are clinically used. Recently, more detailed structural information for cannabinoid receptors was revealed thanks to the powerfulness of cryo-electron microscopy, which now can accelerate structure-based drug discovery. At the same time, novel peptide-type cannabinoids from animal sources have arrived at the scene, with their potential

Indexed as

AnimalsBiological ProductsCannabinoid Receptor AgonistsCannabinoid Receptor AntagonistsCannabinoidsDrug DiscoveryHumansMolecular Docking SimulationPeptidesReceptors, CannabinoidBiological ProductsCannabinoid Receptor AgonistsCannabinoid Receptor AntagonistsCannabinoidsPeptidesReceptors, Cannabinoidanimal venomscannabinoid receptor type 1 (CB1) and type 2 (CB2)phytocannabinoidsstructural analysissynthetic cannabinoids

Identifiers

PMID32709050
PMCPMC7404216
OpenAlexW3043020437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.