Evidence map›Paper›PMID 32709039›Full record

ArticleMetabolites2020

Optimized Protocol for the In Situ Derivatization of Glutathione with

Xueni Sun, Raffaela S Berger, Paul Heinrich, Ibtissam Marchiq, Jacques Pouyssegur, Kathrin Renner, Peter J Oefner, Katja Dettmer

Abstract read
In one paragraph

Article in Metabolites, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  3. Best practices for cysteine analysis.Ferroptosis and oxidative stress · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xueni SunInstitute of Functional Genomics, University of Regensburg, Am BioPark 9, 93053 Regensburg, Germany.
Raffaela S BergerInstitute of Functional Genomics, University of Regensburg, Am BioPark 9, 93053 Regensburg, Germany.
Paul HeinrichInstitute of Functional Genomics, University of Regensburg, Am BioPark 9, 93053 Regensburg, Germany.
Ibtissam MarchiqUniversity Côte d'Azur (IRCAN), CNRS-INSERM, Centre A. Lacassagne, 06189 Nice, France.
Jacques PouyssegurUniversity Côte d'Azur (IRCAN), CNRS-INSERM, Centre A. Lacassagne, 06189 Nice, France.ORCID 0000-0003-2779-6902
Kathrin RennerDepartment of Internal Medicine III, University Hospital Regensburg, 93042 Regensburg, Germany.
Peter J OefnerInstitute of Functional Genomics, University of Regensburg, Am BioPark 9, 93053 Regensburg, Germany.
Katja DettmerInstitute of Functional Genomics, University of Regensburg, Am BioPark 9, 93053 Regensburg, Germany.ORCID 0000-0001-7337-2380

Funding

Interreg V BY-CZ118
6 · The paper itself

Abstract

Glutathione (GSH) and glutathione disulfide (GSSG) are commonly used to assess the oxidative status of a biological system. Various protocols are available for the analysis of GSH and GSSG in biomedical specimens. In this study, we present an optimized protocol for the in situ derivatization of GSH with

Indexed as

cell cultureglutathioneglutathione disulfideliquid chromatographymass spectrometryUV detection

Identifiers

PMID32709039
PMCPMC7407321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.