Evidence map›Paper›PMID 32709019›Full record

ReviewCells2020

CD38: T Cell Immuno-Metabolic Modulator.

Anwesha Kar, Shikhar Mehrotra, Shilpak Chatterjee

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Inhibition of CD38 by 78c Enhanced NADInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Circulating CD38Scientific reports · 2026
    Article
  5. Article
  6. Article
  7. Peripheral Immune Remodeling After Spinal Cord Injury: Marked by Expansion of CD38Neurology(R) neuroimmunology & neuroinflammation · 2026
    Observational
  8. Article
  9. Article
  10. Article
  11. Review
  12. CD38 connects the heart and brain.Translational psychiatry · 2025
    Review
  13. Article
  14. NAD + metabolism and function in innate and adaptive immune cells.Journal of inflammation (London, England) · 2025
    Review
  15. Article
  16. Article
  17. Inhibition of CD38 by 78c Enhanced NADInternational journal of molecular sciences · 2025
    Article
  18. Article
  19. Deciphering the immunomodulatory mechanisms ofFrontiers in cell and developmental biology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Anwesha KarCancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Shikhar MehrotraDepartment of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Shilpak ChatterjeeCancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.ORCID 0000-0002-8428-6434
Indian Institute of Chemical Biology · INMedical University of South Carolina · US

Funding

Anti-oxidant and Metabolic Phenotype in Regulating Tumor Specific T cell Memory ResponseR01CA236379 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MEHROTRA, SHIKHAR · 2020 to 2024
$2.5M
Understanding Metabolic and Epigenetic Cross‐ talk in Potent Anti‐ tumor T cellsR01CA250458 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MEHROTRA, SHIKHAR · 2020 to 2024
$2.3M
Oxidative stress and AICD in memory T cell persistenceR01CA138930 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MEHROTRA, SHIKHAR · 2010 to 2014
$1.5M
NCI NIH HHS R01 CA138930NCI NIH HHS R01 CA236379NCI NIH HHS R01 CA250458
6 · The paper itself

Abstract

Activation and subsequent differentiation of T cells following antigenic stimulation are triggered by highly coordinated signaling events that lead to instilling cells with a discrete metabolic and transcriptional feature. Compelling studies indicate that intracellular nicotinamide adenine dinucleotide (NAD

Indexed as

ADP-ribosyl Cyclase 1AnimalsDiseaseHealthHumansNADSignal TransductionT-LymphocytesADP-ribosyl Cyclase 1NADCD38chromatin remodelingmetabolismNAD+, T cell differentiation

Identifiers

PMID32709019
PMCPMC7408359
OpenAlexW3043098037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.