Evidence map›Paper›PMID 32708978›Full record

ArticleNutrients2020

Circulating Short-Chain Fatty Acids Are Positively Associated with Adiposity Measures in Chinese Adults.

Yiqing Wang, Huijun Wang, Annie Green Howard, Katie A Meyer, Matthew C B Tsilimigras, Christy L Avery, Wei Sha, Shan Sun, Jiguo Zhang, Chang Su and 4 more

Abstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Impacts of Lifestyle and Microbiota-Targeted Interventions for Overweight and Obesity on the Human Gut Microbiome: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
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  8. Observational
  9. The Impact ofMicroorganisms · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yiqing WangDepartment of Nutrition, Gillings School of Global Public Health & School of Medicine, University of North Carolina at Chapel Hill (UNC-Chapel Hill), Chapel Hill, NC 27599, USA.
Huijun WangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Annie Green HowardDepartment of Biostatistics, Gillings School of Global Public Health, UNC-Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0003-0837-8166
Katie A MeyerDepartment of Nutrition, Gillings School of Global Public Health & School of Medicine, University of North Carolina at Chapel Hill (UNC-Chapel Hill), Chapel Hill, NC 27599, USA.
Matthew C B TsilimigrasDepartment of Nutrition, Gillings School of Global Public Health & School of Medicine, University of North Carolina at Chapel Hill (UNC-Chapel Hill), Chapel Hill, NC 27599, USA.
Christy L AveryCarolina Population Center, UNC-Chapel Hill, Chapel Hill, NC 27516, USA.ORCID 0000-0002-1044-8162
Wei ShaDepartment of Cancer Biostatistics, Levine Cancer Institute, Atrium Health, Charlotte, NC 28204, USA.
Shan SunDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte (UNCC), Charlotte, NC 28223, USA.
Jiguo ZhangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 102206, China.ORCID 0000-0003-3266-8999
Chang SuNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Zhihong WangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Bing ZhangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Anthony A FodorDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte (UNCC), Charlotte, NC 28223, USA.
Penny Gordon-LarsenDepartment of Nutrition, Gillings School of Global Public Health & School of Medicine, University of North Carolina at Chapel Hill (UNC-Chapel Hill), Chapel Hill, NC 27599, USA.ORCID 0000-0003-1984-1777

Funding

MONITORING SOCIAL CHANGE: HEALTH, REPRODUCTION, AGINGR01HD030880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ADAIR, LINDA S, POPKIN, BARRY M · 1994 to 2024
$27.0M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Program Development (Pilot) CoreP30AG066615 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELIZABETH A FRANKENBERG · 2020 to 2026
$4.1M
The Genetic Epidemiology of Heart, Lung, and Blood TraitsTraining Grant (GenHLB)T32HL129982 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Christy Leigh Avery, KAREN L. MOHLKE · 2016 to 2026
$3.8M
Monitoring Social Change: Dynamics Of Aging And Cognitive FunctionR01AG065357 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ADAIR, LINDA S, POPKIN, BARRY M · 2020 to 2024
$3.6M
Transition to a Western diet and cardiometabolic risk: biomarkers derived from the microbiomeR01DK104371 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORDON-LARSEN, PENNY · 2015 to 2018
$2.5M
Nutrition-Related NCD Prevention Training in ChinaD43TW009077 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI POPKIN, BARRY M · 2011 to 2015
$1.1M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01 HD30880FIC NIH HHS D43 TW009077NHLBI NIH HHS T32HL129982NIA NIH HHS R01 AG065357NICHD NIH HHS P2C HD050924NICHD NIH HHS R01 HD030880NIDDK NIH HHS R01 DK104371NIDDK NIH HHS R01- DK104371Sanofi 29230-50347-466001
6 · The paper itself

Abstract

Epidemiological studies suggest a positive association between obesity and fecal short-chain fatty acids (SCFAs) produced by microbial fermentation of dietary carbohydrates, while animal models suggest increased energy harvest through colonic SCFA production in obesity. However, there is a lack of human population-based studies with dietary intake data, plasma SCFAs, gut microbial, and anthropometric data. In 490 Chinese adults aged 30-68 years, we examined the associations between key plasma SCFAs (butyrate/isobutyrate, isovalerate, and valerate measured by non-targeted plasma metabolomics) with body mass index (BMI) using multivariable-adjusted linear regression. We then assessed whether overweight (BMI ≥ 24 kg/m

Indexed as

AdiposityAsian PeopleAdultAgedBody Mass IndexColonCross-Sectional StudiesDietDietary CarbohydratesDietary FiberExerciseFatty Acids, VolatileFemaleFermentationGastrointestinal MicrobiomeHumansDietary CarbohydratesDietary FiberFatty Acids, VolatileBMIfibergut metagenomeshort-chain fatty acidswaist-to-height ratio

Identifiers

PMID32708978
PMCPMC7400849

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.