Evidence map›Paper›PMID 32708785›Full record

ReviewMolecules (Basel, Switzerland)2020

Relevant Applications of Generative Adversarial Networks in Drug Design and Discovery: Molecular

Eugene Lin, Chieh-Hsin Lin, Hsien-Yuan Lane

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Artificial Intelligence Across the Drug Development Lifecycle.Medical sciences (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Generative Artificial Intelligence for Virology.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eugene LinDepartment of Biostatistics, University of Washington, Seattle, WA 98195, USA.
Chieh-Hsin LinGraduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Hsien-Yuan LaneGraduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0003-2162-8174

Funding

China Medical University Hospital, Taiwan DMR-HHC-109-13Ministry of Science and Technology, Taiwan MOST 108-2314-B-039-002Ministry of Science and Technology, Taiwan MOST 108-2622-B-039-001-CC2Ministry of Science and Technology, Taiwan MOST 109-2312-B-039-001Ministry of Science and Technology, Taiwan MOST 109-2622-B-039-001-CC2National Health Research Institutes NHRI-EX109-10731NI
6 · The paper itself

Abstract

A growing body of evidence now suggests that artificial intelligence and machine learning techniques can serve as an indispensable foundation for the process of drug design and discovery. In light of latest advancements in computing technologies, deep learning algorithms are being created during the development of clinically useful drugs for treatment of a number of diseases. In this review, we focus on the latest developments for three particular arenas in drug design and discovery research using deep learning approaches, such as generative adversarial network (GAN) frameworks. Firstly, we review drug design and discovery studies that leverage various GAN techniques to assess one main application such as molecular

Indexed as

Drug DesignDrug DiscoveryAlgorithmsArtificial IntelligenceHumansMachine LearningNeural Networks, ComputerPeptidesProteinsPeptidesProteinsartificial intelligencedeep learningde novo peptide and protein designdimension reductiondrug designgenerative adversarial networksmachine learningmolecular de novo designsingle-cell RNA sequencing

Identifiers

PMID32708785
PMCPMC7397124

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.