Evidence map›Paper›PMID 32708666›Full record

ArticleInternational journal of molecular sciences2020

Human Papillomavirus 16-Transgenic Mice as a Model to Study Cancer-Associated Cachexia.

Sara Peixoto da Silva, Joana M O Santos, Verónica F Mestre, Beatriz Medeiros-Fonseca, Paula A Oliveira, Margarida M S M Bastos, Rui M Gil da Costa, Rui Medeiros

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sara Peixoto da SilvaMolecular Oncology and Viral Pathology Group, IPO Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO Porto), 4200-072 Porto, Portugal.ORCID 0000-0003-2030-6368
Joana M O SantosMolecular Oncology and Viral Pathology Group, IPO Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO Porto), 4200-072 Porto, Portugal.ORCID 0000-0002-6268-524X
Verónica F MestreDepartment of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), 5001-801 Vila Real, Portugal.
Beatriz Medeiros-FonsecaDepartment of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), 5001-801 Vila Real, Portugal.
Paula A OliveiraDepartment of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), 5001-801 Vila Real, Portugal.ORCID 0000-0001-9519-4044
Margarida M S M BastosLEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal.
Rui M Gil da CostaMolecular Oncology and Viral Pathology Group, IPO Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO Porto), 4200-072 Porto, Portugal.ORCID 0000-0002-2151-2449
Rui MedeirosMolecular Oncology and Viral Pathology Group, IPO Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO Porto), 4200-072 Porto, Portugal.ORCID 0000-0003-3010-8373
University of Trás-os-Montes and Alto Douro · PTUniversidade do Porto · PTFernando Pessoa University · PT

Funding

Fundação para a Ciência e a Tecnologia SFRH/BD/135871/2018Fundação para a Ciência e a Tecnologia UID/AGR/04033/2019Fundação para a Ciência e a Tecnologia UIDB/00511/2020Instituto Português de Oncologia do Porto PI127-CI-IPOP-118-2019Instituto Português de Oncologia do Porto PI86-CI-IPOP-66-2017Liga Portuguesa Contra o Cancro -
6 · The paper itself

Abstract

Cancer cachexia is a multifactorial syndrome characterized by general inflammation, weight loss and muscle wasting, partly mediated by ubiquitin ligases such as atrogin-1, encoded by

Indexed as

AnimalsBody WeightCachexiaDisease Models, AnimalGene ExpressionHuman papillomavirus 16HumansMaleMice, TransgenicMuscle ProteinsNeoplasmsPapillomavirus InfectionsSKP Cullin F-Box Protein LigasesFbxo32 protein, mouseMuscle ProteinsSKP Cullin F-Box Protein Ligasescancer cachexiaDMBAHPV16K14-HPV16mouse modelwasting syndrome

Identifiers

PMID32708666
PMCPMC7404304
OpenAlexW3043424327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.