Evidence map›Paper›PMID 32708546›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Structural and Bioactivity Characterization of Filipin Derivatives from Engineered

Eva G Barreales, Ángel Rumbero, Tamara D Payero, Antonio de Pedro, Ester Jambrina, Jesús F Aparicio

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eva G BarrealesDepartment of Molecular Biology, Area of Microbiology, Faculty of Biology, Universidad de León, 24071 León, Spain.ORCID 0000-0003-1913-1388
Ángel RumberoDepartment of Organic Chemistry, Faculty of Sciences, Campus de Cantoblanco, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Tamara D PayeroDepartment of Molecular Biology, Area of Microbiology, Faculty of Biology, Universidad de León, 24071 León, Spain.
Antonio de PedroDepartment of Molecular Biology, Area of Microbiology, Faculty of Biology, Universidad de León, 24071 León, Spain.
Ester JambrinaDepartment of Molecular Biology, Area of Microbiology, Faculty of Biology, Universidad de León, 24071 León, Spain.
Jesús F AparicioDepartment of Molecular Biology, Area of Microbiology, Faculty of Biology, Universidad de León, 24071 León, Spain.ORCID 0000-0003-4242-4701
Universidad de León · ESUniversidad Autónoma de Madrid · ES

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España BIO2013-42983-PMinisterio de Economía, Industria y Competitividad, Gobierno de España PCIN-2016-190
6 · The paper itself

Abstract

The rise in the number of immunocompromised patients has led to an increased incidence of fungal infections, with high rates of morbidity and mortality. Furthermore, misuse of antifungals has boosted the number of resistant strains to these agents; thus, there is urgent need for new drugs against these infections. Here, the in vitro antifungal activity of filipin III metabolic intermediates has been characterized against a battery of opportunistic pathogenic fungi-

Indexed as

antifungal agentpolyene macrolideStreptomyces filipinensis

Identifiers

PMID32708546
PMCPMC7400637
OpenAlexW3043616582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.