Evidence map›Paper›PMID 32708371›Full record

ArticlePolymers2020

A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment.

Mireia Andonegi, Ainhoa Irastorza, Ander Izeta, Sara Cabezudo, Koro de la Caba, Pedro Guerrero

Abstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mireia AndonegiBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0001-7250-3051
Ainhoa IrastorzaBiodonostia Health Research Institute, Tissue Engineering Group, Pº Dr. Beguiristain s/n, 20014 Donostia-San Sebastián, Spain.ORCID 0000-0002-1091-8654
Ander IzetaBiodonostia Health Research Institute, Tissue Engineering Group, Pº Dr. Beguiristain s/n, 20014 Donostia-San Sebastián, Spain.ORCID 0000-0003-1879-7401
Sara CabezudoBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0001-7591-4120
Koro de la CabaBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-8866-7314
Pedro GuerreroBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-9785-7048

Funding

Eusko Jaurlaritza 38-2018-00037Eusko Jaurlaritza PRE_2017_1_0025Eusko Jaurlaritza PRE_2019_1_0031Ministerio de Ciencia, Innovación y Universidades RTI2018-097100-B-C22
6 · The paper itself

Abstract

Native collagen scaffolds were prepared in this work, in which both materials and environmental approaches were considered with the aim of providing a global strategy towards more sustainable biomaterials. From the environmental perspective, it is worth mentioning that acid and enzymatic treatments have been avoided to extract collagen, allowing the reduction in the use of resources, in terms of chemicals, energy, and time, and leading to a low environmental load of this step in all the impact categories under analysis. With the incorporation of chitosan into the scaffold-forming formulations, physical interactions occurred between collagen and chitosan, but the native collagen structure was preserved, as observed by Fourier transform infrared (FTIR) and X-ray diffraction (XRD) analyses. The incorporation of chitosan also led to more homogenous porous microstructures, with higher elastic moduli and compression resistance for both dry and hydrated scaffolds. Furthermore, hydrated scaffolds preserved their size and shape after some compression cycles.

Indexed as

chitosandegradationenvironmental assessmentnative collagenscaffolds

Identifiers

PMID32708371
PMCPMC7408220

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.