ReviewBiomedicines2020
Asthma and Obesity in Children.
Review in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 44 citations in OpenAlex.
- The impact of obesity-related asthma on neurodevelopmental disorders in children: a cross-sectional study.Pediatric research · 2026Article
- A Multi-Omics Approach Uncovers Divergent Mechanisms of Asthma in Normal Weight and Obese Children.Metabolites · 2026Article
- Relationship between BMI-SDS trajectories and childhood asthma: a prospective cohort study from the Japan Environment and Children's Study.Environmental health and preventive medicine · 2026Article
- Dietary Habits and Their Impact on Pediatric Obesity and Asthma: A Narrative Review with Emphasis on the Mediterranean Diet.Children (Basel, Switzerland) · 2025Review
- Mediating role of basophils in the triacylglycerol-asthma link: a Mendelian randomization study.3 Biotech · 2025Article
- Article
- Alterations of DNA methylation profile in peripheral blood of children with simple obesity.Health information science and systems · 2024Article
- Investigating the relationship between asthma symptoms and severity with television watching, computer use, and internet access among 13-14-year-old children in Yazd, Iran.BMC pediatrics · 2024Article
- Exploring the Link between Oxidative Stress, Selenium Levels, and Obesity in Youth.International journal of molecular sciences · 2024Review
- Pediatric asthma comorbidities: Global impact and unmet needs.The World Allergy Organization journal · 2024Review
- Beyond the Metabolic Syndrome: Non-Obvious Complications of Obesity in Children.Children (Basel, Switzerland) · 2023Review
- Breast feeding, obesity, and asthma association: clinical and molecular views.Clinical and molecular allergy : CMA · 2023Review
- Mediterranean Diet and Airway Inflammation in School-Aged Children.Children (Basel, Switzerland) · 2023Article
- Allergic Diseases and Childhood Obesity: A Detrimental Link?Biomedicines · 2023Review
- Article
- Whole Blood Expression Levels of Long Noncoding RNAs: HOTAIRM1, GAS5, MZF1-AS1, and OIP5-AS1 as Biomarkers in Adolescents with Obesity-Related Asthma.International journal of molecular sciences · 2023Article
- Early-life weight gain is associated with non-atopic asthma in childhood.The World Allergy Organization journal · 2022Article
- Impact of Obesity on Lung Function in Cats with Bronchoconstriction.Veterinary sciences · 2022Article
- Insulin-resistance in paediatric age: Its magnitude and implications.World journal of diabetes · 2022Review
- An Overview of the Obese-Asthma Phenotype in Children.International journal of environmental research and public health · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma and obesity are two major chronic diseases in children and adolescents. Recent scientific evidence points out a causative role of obesity in asthma predisposition. However, studies assessing the real impact of excessive weight gain on lung function in children have shown heterogeneous results. In this review, the pathological mechanisms linking obesity and development of asthma in children are summarized and factors influencing this relationship are evaluated. Common disease modifying factors including age, sex, ethnicity, development of atopic conditions, and metabolic alterations significantly affect the onset and phenotypic characteristics of asthma. Given this, the impact of these several factors on the obesity-asthma link were considered, and from revision of the literature we suggest the possibility to define three main clinical subtypes on the basis of epidemiological data and physiological-molecular pathways: obese-asthmatic and atopy, obese-asthmatic and insulin-resistance, and obese-asthmatic and dyslipidemia. The hypothesis of the different clinical subtypes characterizing a unique phenotype might have an important impact for both future clinical management and research priorities. This might imply the necessity to study the obese asthmatic child with a "multidisciplinary approach", evaluating the endocrinological and pneumological aspects simultaneously. This different approach might also make it possible to intervene earlier in a specific manner, possibly with a personalized and tailored treatment. Surely this hypothesis needs longitudinal and well-conducted future studies to be validated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.