Evidence map›Paper›PMID 32708138›Full record

ReviewCancers2020

Anti-Cancer Potential of Cannabinoids, Terpenes, and Flavonoids Present in Cannabis.

Andrea M Tomko, Erin G Whynot, Lee D Ellis, Denis J Dupré

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 215 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Integrated Computational Investigation ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  11. Article
  12. Review
  13. Potential Anticancer Effect ofInternational journal of molecular sciences · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrea M TomkoDepartment of Pharmacology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Erin G WhynotDepartment of Pharmacology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Lee D EllisAquatic and Crop Resource Development Research Center, National Research Council of Canada, Halifax, NS B3H 3Z1, Canada.
Denis J DupréDepartment of Pharmacology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0001-6401-6157
Dalhousie University · CANational Research Council Canada · CA

Funding

Beatrice Hunter Cancer Research Institute seed fundingFaculty of Medicine, Dalhousie University bridge funding
6 · The paper itself

Abstract

In recent years, and even more since its legalization in several jurisdictions, cannabis and the endocannabinoid system have received an increasing amount of interest related to their potential exploitation in clinical settings. Cannabinoids have been suggested and shown to be effective in the treatment of various conditions. In cancer, the endocannabinoid system is altered in numerous types of tumours and can relate to cancer prognosis and disease outcome. Additionally, cannabinoids display anticancer effects in several models by suppressing the proliferation, migration and/or invasion of cancer cells, as well as tumour angiogenesis. However, the therapeutic use of cannabinoids is currently limited to the treatment of symptoms and pain associated with chemotherapy, while their potential use as cytotoxic drugs in chemotherapy still requires validation in patients. Along with cannabinoids, cannabis contains several other compounds that have also been shown to exert anti-tumorigenic actions. The potential anti-cancer effects of cannabinoids, terpenes and flavonoids, present in cannabis, are explored in this literature review.

Indexed as

cancercannabinoidcannabiscytotoxicityentourage effectflavonoidterpene

Identifiers

PMID32708138
PMCPMC7409346
OpenAlexW3045475100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.