Evidence map›Paper›PMID 32708014›Full record

ArticleInternational journal of molecular sciences2020

Diabetes Mellitus and Hypertension-A Case of Sugar and Salt?

Marcus Sondermann, Michał Holecki, Andrea Marita Kirsch, Manuela Bastian, Dagmar-Christiane Fischer, Holger Sven Willenberg

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Marcus SondermannDivision of Endocrinology and Metabolism, Rostock University Medical Center, 18057 Rostock, Germany.
Michał HoleckiDepartment of Internal, Autoimmune and Metabolic Diseases, Medical Faculty in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0002-3289-1050
Andrea Marita KirschDivision of Endocrinology and Metabolism, Rostock University Medical Center, 18057 Rostock, Germany.
Manuela BastianInstitute for Clinical Chemistry and Laboratory Medicine, Rostock University Medical Center, 18057 Rostock, Germany.
Dagmar-Christiane FischerDepartment of Pediatrics, Rostock University Medical Centre, Rostock, 18057 Rostock, Germany.
Holger Sven WillenbergDivision of Endocrinology and Metabolism, Rostock University Medical Center, 18057 Rostock, Germany.
University of Rostock · DEMedical University of Silesia · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of patients with diabetes mellitus (DM) have hypertension (HTN). A specific mechanism for the development of HTN in DM has not been described. In the Zucker, Endothel, und Salz (sugar, endothelium, and salt) study (ZEuS), indices of glucose metabolism and of volume regulation are recorded. An analysis of these parameters shows that glucose concentrations interfere with plasma osmolality and that changes in glycemic control have a significant impact on fluid status and blood pressure. The results of this study are discussed against the background of the striking similarities between the regulation of sugar and salt blood concentrations, introducing the view that DM is probably a sodium-retention disorder that leads to a state of hypervolemia.

Indexed as

AdultAgedBlood PressureDiabetes Mellitus, Type 2FemaleHumansHypertensionMaleMiddle AgedOsmolar ConcentrationSodium Chloride, DietarySugarsSodium Chloride, DietarySugarsadrenalaldosteronecortisoldiabetes mellitusglucosehypertensionosmolalitySGLT2sodiumwater homeostasis

Identifiers

PMID32708014
PMCPMC7432106
OpenAlexW3044097304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.