Evidence map›Paper›PMID 32707988›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Graphene Oxide-Linezolid Combination as Potential New Anti-Tuberculosis Treatment.

Flavio De Maio, Valentina Palmieri, Giulia Santarelli, Giordano Perini, Alessandro Salustri, Ivana Palucci, Michela Sali, Jacopo Gervasoni, Aniello Primiano, Gabriele Ciasca and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Flavio De MaioDipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario "A. Gemelli" IRCSS, 00168 Rome, Italy.ORCID 0000-0002-4744-9820
Valentina PalmieriDipartimento di Neuroscienze, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.ORCID 0000-0002-6358-9647
Giulia SantarelliDipartimento di Scienze biotecnologiche di base, cliniche intensivologiche e perioperatorie-Sezione di Microbiologia, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Giordano PeriniDipartimento di Neuroscienze, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.ORCID 0000-0001-9452-8479
Alessandro SalustriDipartimento di Scienze biotecnologiche di base, cliniche intensivologiche e perioperatorie-Sezione di Microbiologia, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Ivana PalucciDipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario "A. Gemelli" IRCSS, 00168 Rome, Italy.
Michela SaliDipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario "A. Gemelli" IRCSS, 00168 Rome, Italy.
Jacopo GervasoniFondazione Policlinico Universitario "A. Gemelli" IRCSS, 00168 Rome, Italy.
Aniello PrimianoFondazione Policlinico Universitario "A. Gemelli" IRCSS, 00168 Rome, Italy.
Gabriele CiascaDipartimento di Neuroscienze, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Maurizio SanguinettiDipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario "A. Gemelli" IRCSS, 00168 Rome, Italy.
Marco De SpiritoDipartimento di Neuroscienze, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Giovanni DeloguDipartimento di Scienze biotecnologiche di base, cliniche intensivologiche e perioperatorie-Sezione di Microbiologia, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Massimiliano PapiDipartimento di Neuroscienze, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Università Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Global pandemic management represents a serious issue for health systems. In some cases, repurposing of existing medications might help find compounds that have the unexpected potential to combat microorganisms. In the same way, changing cell-drug interaction by nanotechnology could represent an innovative strategy to fight infectious diseases. Tuberculosis (TB) remains one of the most alarming worldwide infectious diseases and there is an urgent need for new drugs and treatments, particularly for the emergence and spread of drug-resistant

Indexed as

graphene oxidelinezolidnanotechnologytherapytrappingtuberculosis

Identifiers

PMID32707988
PMCPMC7466666
OpenAlexW3044528786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.