Evidence map›Paper›PMID 32707947›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Antitumoral Drug Potential of Tryptophan-Betaxanthin and Related Plant Betalains in the

Paula Henarejos-Escudero, Samanta Hernández-García, M Alejandra Guerrero-Rubio, Francisco García-Carmona, Fernando Gandía-Herrero

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Identification ofPlant biotechnology (Tokyo, Japan) · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Biological Properties and Applications of Betalains.Molecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Paula Henarejos-EscuderoDepartamento de Bioquímica y Biología Molecular A, Unidad Docente de Biología, Facultad de Veterinaria, Regional Campus of International Excellence "Campus Mare Nostrum″, Universidad de Murcia, 30100 Murcia, Spain.
Samanta Hernández-GarcíaDepartamento de Bioquímica y Biología Molecular A, Unidad Docente de Biología, Facultad de Veterinaria, Regional Campus of International Excellence "Campus Mare Nostrum″, Universidad de Murcia, 30100 Murcia, Spain.ORCID 0000-0002-6944-0050
M Alejandra Guerrero-RubioDepartamento de Bioquímica y Biología Molecular A, Unidad Docente de Biología, Facultad de Veterinaria, Regional Campus of International Excellence "Campus Mare Nostrum″, Universidad de Murcia, 30100 Murcia, Spain.
Francisco García-CarmonaDepartamento de Bioquímica y Biología Molecular A, Unidad Docente de Biología, Facultad de Veterinaria, Regional Campus of International Excellence "Campus Mare Nostrum″, Universidad de Murcia, 30100 Murcia, Spain.
Fernando Gandía-HerreroDepartamento de Bioquímica y Biología Molecular A, Unidad Docente de Biología, Facultad de Veterinaria, Regional Campus of International Excellence "Campus Mare Nostrum″, Universidad de Murcia, 30100 Murcia, Spain.
Universidad de Murcia · ES

Funding

Fundación Séneca Project 19893/GERM/15Ministerio de Economía y Competitividad AGL2017-86526Wellcome Trust
6 · The paper itself

Abstract

Betalains are plants pigments identified as potent antioxidant molecules, naturally present in foods like beetroot and prickly pears. Although activities described for betalain-containing formulations include cancer prevention and treatment, the use of extracts instead of purified pigments has avoided the investigation of the real chemopreventive and chemotherapeutic potential of these phytochemicals. Three betalain-rich extracts and six individual pure betalains were used in this work to characterize the activity and to explore possible molecular mechanisms. The animal model

Indexed as

AntitumoralbetalainsC. eleganschemotherapyphytochemicaltryptophan-betaxanthin

Identifiers

PMID32707947
PMCPMC7465535
OpenAlexW3044940536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.