Evidence map›Paper›PMID 32707824›Full record

ArticleInternational journal of molecular sciences2020

Assessing Molecular Docking Tools to Guide Targeted Drug Discovery of CD38 Inhibitors.

Eric D Boittier, Yat Yin Tang, McKenna E Buckley, Zachariah P Schuurs, Derek J Richard, Neha S Gandhi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 74 citations in OpenAlex.

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  4. Differential Evolution for Docking Simulations.Methods in molecular biology (Clifton, N.J.) · 2026
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  9. Potential Antidiabetic Inhibitors and Antimicrobials from the FungusJournal of microbiology and biotechnology · 2025
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  13. Virtual screening: hope, hype, and the fine line in between.Expert opinion on drug discovery · 2025
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  16. EXCLI journal · 2024
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  18. The Search for Antidotes Against Ricin.Mini reviews in medicinal chemistry · 2024
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  19. Synthesis of Pyrrolo[3,4-Pharmaceuticals (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eric D BoittierCancer & Ageing Research Program, Institute of Health and Biomedical Innovation at the Translational Research Institute (TRI), Queensland University of Technology (QUT), Brisbane, Queensland 4102, Australia.
Yat Yin TangCancer & Ageing Research Program, Institute of Health and Biomedical Innovation at the Translational Research Institute (TRI), Queensland University of Technology (QUT), Brisbane, Queensland 4102, Australia.
McKenna E BuckleySchool of Chemistry and Physics, Faculty of Science and Engineering, Queensland University of Technology, Brisbane, QLD 4000, Australia.ORCID 0000-0002-3177-5234
Zachariah P SchuursCancer & Ageing Research Program, Institute of Health and Biomedical Innovation at the Translational Research Institute (TRI), Queensland University of Technology (QUT), Brisbane, Queensland 4102, Australia.
Derek J RichardCancer & Ageing Research Program, Institute of Health and Biomedical Innovation at the Translational Research Institute (TRI), Queensland University of Technology (QUT), Brisbane, Queensland 4102, Australia.
Neha S GandhiCancer & Ageing Research Program, Institute of Health and Biomedical Innovation at the Translational Research Institute (TRI), Queensland University of Technology (QUT), Brisbane, Queensland 4102, Australia.ORCID 0000-0003-3119-6731
Translational Research Institute · AUQueensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A promising protein target for computational drug development, the human cluster of differentiation 38 (CD38), plays a crucial role in many physiological and pathological processes, primarily through the upstream regulation of factors that control cytoplasmic Ca

Indexed as

ADP-ribosyl Cyclase 1AlgorithmsBinding SitesDatabases, ProteinDrug DiscoveryEnzyme InhibitorsLigandsMachine LearningMembrane GlycoproteinsMolecular Docking SimulationProtein ConformationSoftwareADP-ribosyl Cyclase 1CD38 protein, humanEnzyme InhibitorsLigandsMembrane GlycoproteinsCD38 (cluster of differentiation 38 protein)drug designenzyme inhibitormolecular dockingscoring functions

Identifiers

PMID32707824
PMCPMC7432575
OpenAlexW3044082277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.