Evidence map›Paper›PMID 32707818›Full record

ArticleInternational journal of molecular sciences2020

Alterations of STEP46 and STEP61 Expression in the Rat Retina with Age and AMD-Like Retinopathy Development.

Darya V Telegina, Elizabeth A Kulikova, Oyuna S Kozhevnikova, Alexander V Kulikov, Tatyana M Khomenko, Konstantin P Volcho, Nariman F Salakhutdinov, Nataliya G Kolosova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Darya V TeleginaInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Pr. Lavrentyeva 10, 630090 Novosibirsk, Russia.ORCID 0000-0001-8096-0519
Elizabeth A KulikovaInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Pr. Lavrentyeva 10, 630090 Novosibirsk, Russia.
Oyuna S KozhevnikovaInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Pr. Lavrentyeva 10, 630090 Novosibirsk, Russia.ORCID 0000-0001-6475-4061
Alexander V KulikovInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Pr. Lavrentyeva 10, 630090 Novosibirsk, Russia.
Tatyana M KhomenkoN.N. Vorozhtsov Institute of Organic Chemistry, SB RAS, 9 Lavrentieva Avenue, 630090 Novosibirsk, Russia.
Konstantin P VolchoN.N. Vorozhtsov Institute of Organic Chemistry, SB RAS, 9 Lavrentieva Avenue, 630090 Novosibirsk, Russia.ORCID 0000-0002-4083-9324
Nariman F SalakhutdinovN.N. Vorozhtsov Institute of Organic Chemistry, SB RAS, 9 Lavrentieva Avenue, 630090 Novosibirsk, Russia.
Nataliya G KolosovaInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Pr. Lavrentyeva 10, 630090 Novosibirsk, Russia.ORCID 0000-0003-2398-8544
Russian Academy of Sciences · RUNovosibirsk Institute of Organic Chemistry · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 14.W03.31.0034Russian Foundation for Basic Research Project for a Young Researcher 0259-2019-0002-c-01
6 · The paper itself

Abstract

Tyrosine phosphatase STEP (striatal-enriched tyrosine protein phosphatase) is a brain-specific protein phosphatase and is involved in the pathogenesis of many neurodegenerative diseases. Here, we examined the impact of STEP on the development of age-related macular degeneration (AMD)-like pathology in senescence-accelerated OXYS rats. Using OXYS and Wistar rats (control), we for the first time demonstrated age-dependent changes in

Indexed as

AgingAnimalsApoptosisBenzothiepinsBrain-Derived Neurotrophic FactorCellular SenescenceGene Expression RegulationMacular DegenerationMaleNerve Growth FactorNeurogliaNeuronsProtein Tyrosine Phosphatases, Non-ReceptorRatsRats, WistarRetina8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amineBdnf protein, ratBenzothiepinsBrain-Derived Neurotrophic FactorNerve Growth FactorProtein Tyrosine Phosphatases, Non-ReceptorPtpn5 protein, ratage-related macular degenerationOXYS ratsPtpn5STEP46STEP61striatal-enriched protein tyrosine phosphataseTC-2153

Identifiers

PMID32707818
PMCPMC7432912
OpenAlexW3045090917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.