Evidence map›Paper›PMID 32707748›Full record

ArticleNutrients2020

Biomarkers of Browning in Cold Exposed Siberian Adults.

Agrafena Efremova, Georgia Colleluori, Mikhail Thomsky, Jessica Perugini, Marina Protasoni, Marcella Reguzzoni, Andrea Faragalli, Flavia Carle, Antonio Giordano, Saverio Cinti

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Biomolecules · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Agrafena EfremovaYakut Scientific Center of Complex Medical Problems, 677010 Yakutsk, Russia.
Georgia ColleluoriCenter for the Study of Obesity, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Via Tronto 10A, 60020 Ancona, Italy.ORCID 0000-0002-4908-9873
Mikhail ThomskyYakut Scientific Center of Complex Medical Problems, 677010 Yakutsk, Russia.
Jessica PeruginiCenter for the Study of Obesity, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Via Tronto 10A, 60020 Ancona, Italy.ORCID 0000-0002-6718-4815
Marina ProtasoniDepartment of Medicine and Surgery, University of Insubria, Via Ravasi 2, 21100 Varese, Italy.
Marcella ReguzzoniDepartment of Medicine and Surgery, University of Insubria, Via Ravasi 2, 21100 Varese, Italy.
Andrea FaragalliCenter of Epidemiology, Biostatistics and Medical Information Technology, Marche Polytechnic University, Via Tronto 10A, 60020 Ancona, Italy.ORCID 0000-0003-4414-4789
Flavia CarleCenter of Epidemiology, Biostatistics and Medical Information Technology, Marche Polytechnic University, Via Tronto 10A, 60020 Ancona, Italy.ORCID 0000-0002-2422-6528
Antonio GiordanoCenter for the Study of Obesity, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Via Tronto 10A, 60020 Ancona, Italy.ORCID 0000-0003-1401-5855
Saverio CintiCenter for the Study of Obesity, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Via Tronto 10A, 60020 Ancona, Italy.ORCID 0000-0003-0362-5017
Marche Polytechnic University · ITUniversity of Insubria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cold-exposure promotes energy expenditure by inducing brown adipose tissue (BAT) thermogenesis, which over time, is also sustained by browning, the appearance, or increase, of brown-like cells into white fat depots. Identification of circulating markers reflecting BAT activity and browning is crucial to study this phenomenon and its triggers, also holding possible implications for the therapy of obesity and metabolic diseases. Using RT-qPCR, we evaluated the peripheral blood mononuclear cells (PBMC) expression profile of regulators of BAT activity (

Indexed as

Cold TemperatureAdipocytes, WhiteAdipose Tissue, BrownAdultAnthropometryApoptosis Regulatory ProteinsBiomarkersCarnitine O-PalmitoyltransferaseCholesterol, HDLCholesterol, LDLCross-Sectional StudiesDNA-Binding ProteinsEnergy MetabolismFatty Acid Transport ProteinsHomeodomain ProteinsHumansApoptosis Regulatory ProteinsBiomarkersCarnitine O-PalmitoyltransferaseCholesterol, HDLCholesterol, LDLCIDEA protein, humanCPT1B protein, humanDNA-Binding ProteinsFatty Acid Transport ProteinsHomeodomain ProteinsHoxc9 protein, humanPRDM16 protein, humanSLC27A1 protein, humanTranscription FactorsTriglyceridesbiomarkersbrown adipose tissuebrowningcold-exposureperipheral blood mononuclear cellsthermogenesis

Identifiers

PMID32707748
PMCPMC7468804
OpenAlexW3044317294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.