Evidence map›Paper›PMID 32707737›Full record

ArticleInternational journal of molecular sciences2020

NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer.

Hsin-Hua Chung, Chun-Te Lee, Je-Ming Hu, Yu-Ching Chou, Ya-Wen Lin, Yu-Lueng Shih

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Metastasis Inhibition.International journal of molecular sciences · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Frontiers in oncology · 2021
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hsin-Hua ChungGraduate Institute of Medical Sciences, National Defense Medical Center, No.161, Sec.6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.ORCID 0000-0001-6872-3684
Chun-Te LeeDivision of Urological Surgery, Department of Surgery, Tri-Service General Hospital Songshan Branch, No.131, Jiankang Rd., Songshan District, Taipei 10581, Taiwan.
Je-Ming HuGraduate Institute of Medical Sciences, National Defense Medical Center, No.161, Sec.6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.
Yu-Ching ChouSchool of Public Health, National Defense Medical Center, No.161, Sec.6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.
Ya-Wen LinGraduate Institute of Medical Sciences, National Defense Medical Center, No.161, Sec.6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.ORCID 0000-0002-1639-7941
Yu-Lueng ShihGraduate Institute of Medical Sciences, National Defense Medical Center, No.161, Sec.6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.ORCID 0000-0003-4629-4393
National Defense Medical Center · TWTri-Service General Hospital · TWTri-Service General Hospital Songshan Branch · TW

Funding

Ministry of National Defense, Taiwan MAB-108-013Ministry of National Defense, Taiwan MAB-108-014Ministry of National Defense, Taiwan MAB-108-015Ministry of National Defense, Taiwan MAB-109-036Ministry of Science and Technology, Taiwan MOST 108-2314-B-016-043-MY2Tri-Service General Hospital Songshan Branch, Taiwan TSGH-SS-D108-39Tri-Service General Hospital Songshan Branch, Taiwan TSGH-SS-D109-007Tri-Service General Hospital, Taiwan TSGH-D109-076
6 · The paper itself

Abstract

Accumulating evidence suggests that NKX6.1 (NK homeobox 1) plays a role in various types of cancer. In our previous studies, we identified

Indexed as

AnimalsBiomarkers, TumorCarcinogenesisCell Line, TumorCell MovementCell Transformation, NeoplasticColorectal NeoplasmsDrug Resistance, NeoplasmEpithelial-Mesenchymal TransitionFemaleFluorouracilGene Expression Regulation, NeoplasticGene Knockdown TechniquesGene OntologyGenes, Tumor SuppressorHCT116 CellsBiomarkers, TumorFluorouracilHomeodomain ProteinsNKX6-1 protein, humanOxaliplatinchemoresistancecolorectal cancer (CRC)epithelial-to-mesenchymal transition (EMT)metastasisNK6 homeobox 1 (NKX6.1)tumor suppressor

Identifiers

PMID32707737
PMCPMC7404324
OpenAlexW3043353112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.