Evidence map›Paper›PMID 32707664›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Effects of Functionalized Fullerenes on ROS Homeostasis Determine Their Cytoprotective or Cytotoxic Properties.

Svetlana V Kostyuk, Elena V Proskurnina, Ekaterina A Savinova, Elizaveta S Ershova, Olga A Kraevaya, Larisa V Kameneva, Pavel E Umryukhin, Olga A Dolgikh, Sergey I Kutsev, Pavel A Troshin and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Cytotoxicity and Genotoxicity of Nanomaterials.Nanomaterials (Basel, Switzerland) · 2022
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Svetlana V KostyukLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.
Elena V ProskurninaLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.ORCID 0000-0002-8243-6339
Ekaterina A SavinovaLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.
Elizaveta S ErshovaLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.
Olga A KraevayaCenter for Energy Science and Technology, Skolkovo Institute of Science and Technology, ul. Nobelya 3, 143026 Moscow, Russia.
Larisa V KamenevaLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.
Pavel E UmryukhinLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.
Olga A DolgikhLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.ORCID 0000-0002-4426-8864
Sergey I KutsevLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.
Pavel A TroshinCenter for Energy Science and Technology, Skolkovo Institute of Science and Technology, ul. Nobelya 3, 143026 Moscow, Russia.
Natalia N VeikoLaboratory of Molecular Biology, Research Centre for Medical Genetics, ul Moskvorechye 1, 115522 Moscow, Russia.
Research Centre for Medical Genetics · RUSechenov University · RUSkolkovo Institute of Science and Technology · RU

Funding

Russian Science Foundation 18-15-00437Russian Science Foundation 19-13-00411
6 · The paper itself

Abstract

backgroundFunctionalized fullerenes (FF) can be considered regulators of intracellular reactive oxygen species (ROS) homeostasis; their direct oxidative damage-as well as regulation of oxidant enzymes and signaling pathways-should be considered.

methodsUptake of two water-soluble functionalized C RESULTS &

conclusionThe intracellular effects of ethylphenylmalonate C

Indexed as

apoptosiscell proliferationcytoprotectioncytotoxicityfunctionalized fullerenesNOX4oxidative DNA damageoxidative stressROS homeostasisROS-signaling

Identifiers

PMID32707664
PMCPMC7407884
OpenAlexW3042985824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.