Evidence map›Paper›PMID 32707345›Full record

ReviewNeuroscience and biobehavioral reviews2020

Human gender development.

Melissa Hines

Abstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Gender Identity and Preferences in Children with Variations in Sex DevelopmentJournal of clinical research in pediatric endocrinology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Sex and gender in neurodevelopmental conditions.Nature reviews. Neurology · 2023
    Review
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Melissa HinesDepartment of Psychology, University of Cambridge, Free School Lane, Cambridge, CB2 3RQ, UK. Electronic address: mh504@cam.ac.uk.

Funding

Brain and behavior in individuals with intersex conditionsR01HD081720 · NICHD · UNIVERSITY OF CAMBRIDGE · PI HINES, MELISSA, LUEDERS, EILEEN · 2015 to 2020
$1.8M
NICHD NIH HHS R01 HD081720
6 · The paper itself

Abstract

Human gender-related behavior/psychology is shaped by a developmental system that involves numerous influences interacting over time. Understanding of the full range of elements in the system and how they interact is currently incomplete. The available evidence suggests, however, that early exposure to testosterone, postnatal socialization, e.g., by parents and peers, and self-socialization related to cognitive understanding of gender are important elements. This article focuses on prenatal and early neonatal influences of testosterone on gender-related psychological/behavioral outcomes, and contextualizes these hormonal influences within an understanding of socialization influences. There is consistent evidence that early testosterone exposure influences childhood gender role behavior, including sex-typical toy play, as well as gender identity and sexual orientation. Evidence for similar hormonal influences on spatial ability and on traits related to autism, or autistic spectrum disorder, is inconsistent. Evidence from girls exposed to elevated testosterone prenatally suggests that they experience alterations in processes of external socialization, as well as self-socialization, and that these, along with early testosterone exposure, shape gender-related outcomes.

Indexed as

Autism Spectrum DisorderGender IdentityChildFemaleHumansInfant, NewbornMaleParentsPregnancySexual BehaviorTestosteroneTestosteroneAndrogenAutismAutistic spectrum disorderAutistic traitsChildhood gender role behaviorGenderGender identityGender role behaviorMental rotationSexSexual orientationSpatial abilityTestosterone

Identifiers

PMID32707345
PMCPMC10691233

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.