Evidence map›Paper›PMID 32707307›Full record

ArticleWater research2020

Making waves: Wastewater surveillance of SARS-CoV-2 for population-based health management.

Janelle R Thompson, Yarlagadda V Nancharaiah, Xiaoqiong Gu, Wei Lin Lee, Verónica B Rajal, Monamie B Haines, Rosina Girones, Lee Ching Ng, Eric J Alm, Stefan Wuertz

Open access · greenAbstract read
In one paragraph

Article in Water research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it, 200 citations in OpenAlex.

  1. Pooled it
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  7. Using Wastewater to Monitor Suggested Changes in Dietary Intake: A Participatory Experiment.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 5 countries.

Janelle R ThompsonSingapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University (NTU), Singapore; Asian School of the Environment, NTU, Singapore; Campus for Research Excellence and Technological Enterprise (CREATE), Singapore. Electronic address: janelle.thompson@ntu.edu.sg.
Yarlagadda V NancharaiahBiofouling and Biofilm Processes, Water and Steam Chemistry Division, Chemistry Group, Bhabha Atomic Research Centre, Kalpakkam 603102, India; Homi Bhabha National Institute, BARC Training School Complex, Anushakti Nagar, Trombay, Mumbai 400 094, India.
Xiaoqiong GuCampus for Research Excellence and Technological Enterprise (CREATE), Singapore; Singapore-MIT Alliance for Research and Technology, National University of Singapore, Singapore.
Wei Lin LeeCampus for Research Excellence and Technological Enterprise (CREATE), Singapore; Singapore-MIT Alliance for Research and Technology, National University of Singapore, Singapore.
Verónica B RajalSingapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University (NTU), Singapore; Instituto de Investigaciones para la Industria Química (INIQUI), CONICET, Universidad Nacional de Salta (UNSa), Av. Bolivia 5150, Salta 4400, Argentina; Facultad de Ingeniería, UNSa, Salta, Argentina.
Monamie B HainesCampus for Research Excellence and Technological Enterprise (CREATE), Singapore; School of Social Sciences, Sociology Division, NTU, Singapore.
Rosina GironesSection of Microbiology, Virology and Biotechnology, Department of Genetics, Microbiology and Statistics, Faculty of Biology, University of Barcelona, Diagonal, 643, 08028-Barcelona, Spain.
Lee Ching NgEnvironmental Health Institute, National Environment Agency, Singapore.
Eric J AlmCampus for Research Excellence and Technological Enterprise (CREATE), Singapore; Singapore-MIT Alliance for Research and Technology, National University of Singapore, Singapore; Center for Microbiome Informatics and Therapeutics, Departments of Biological Engineering and Civil and Environmental Engineering, Massachusetts Institute of Technology, United States; Biobot Analytics, Cambridge MA, United States.
Stefan WuertzSingapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University (NTU), Singapore; Campus for Research Excellence and Technological Enterprise (CREATE), Singapore; School of Civil and Environmental Engineering, NTU, Singapore. Electronic address: swuertz@ntu.edu.sg.
National University of Singapore · SGNanyang Technological University · SGBhabha Atomic Research Centre · INNational Environment Agency · SGNational University of Salta · ARSingapore-HUJ Alliance for Research and Enterprise · SGUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, clinical data remain the gold standard for disease surveillance and tracking. However, such data are limited due to factors such as reporting bias and inability to track asymptomatic disease carriers. Disease agents are excreted in the urine and feces of infected individuals regardless of disease symptom severity. Wastewater surveillance - that is, monitoring disease via human effluent - represents a valuable complement to clinical approaches. Because wastewater is relatively inexpensive and easy to collect and can be monitored at different levels of population aggregation as needed, wastewater surveillance can offer a real-time, cost-effective view of a community's health that is independent of biases associated with case-reporting. For SARS-CoV-2 and other disease-causing agents we envision an aggregate wastewater-monitoring system at the level of a wastewater treatment plant and exploratory or confirmatory monitoring of the sewerage system at the neighborhood scale to identify or confirm clusters of infection or assess impact of control measures where transmission has been established. Implementation will require constructing a framework with collaborating government agencies, public or private utilities, and civil society organizations for appropriate use of data collected from wastewater, identification of an appropriate scale of sample collection and aggregation to balance privacy concerns and risk of stigmatization with public health preservation, and consideration of the social implications of wastewater surveillance.

Indexed as

BetacoronavirusCoronavirus InfectionsPandemicsPneumonia, ViralWastewaterCOVID-19HumansSARS-CoV-2WastewaterData privacyFecal-oral transmissionHealth managementSARS-CoV-2Wastewater surveillance

Identifiers

PMID32707307
PMCPMC7357518
OpenAlexW3041187075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.