Evidence map›Paper›PMID 32707283›Full record

ReviewInternational journal of biological macromolecules2020

Lactoferrin, a unique molecule with diverse therapeutical and nanotechnological applications.

Sally Sabra, Mona M Agwa

Open access · bronzeAbstract readReview
In one paragraph

Review in International journal of biological macromolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 100 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. ExploringACS omega · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Progress of nanoparticle drug delivery system for the treatment of glioma.Frontiers in bioengineering and biotechnology · 2024
    Review
  18. Lactoferrin, the Moonlighting Protein of Innate Immunity.International journal of molecular sciences · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sally SabraDepartment of Biotechnology, Institute of Graduate studies and Research, Alexandria University, Alexandria 21526, Egypt. Electronic address: ssabra@uwo.ca.
Mona M AgwaDepartment of Chemistry of Natural and Microbial Products, Pharmaceutical and Drug Industries Research Division, National Research Centre, 33 El-Behooth St, Dokki, Giza 12311, Egypt. Electronic address: mona.m.agwa@alexu.edu.eg.
Alexandria University · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactoferrin (LF) is a naturally glycoprotein with iron-binding properties and diverse biological applications including; antiviral, anti-inflammatory, antioxidant, anti-cancer and immune stimulating effects. In addition, LF was found to be an ideal nanocarrier for some hydrophobic therapeutics because of its active targeting potential due to overexpression of its receptor on the surface of many cells. Moreover, it was proven to be a good candidate for fabrication of nanocarriers to specifically deliver drugs in case of brain tumors owing to the capability of LF to cross the blood brain barrier (BBB). Consequently, it seems to be a promising molecule with multiple applications in the field of cancer therapy and nanomedicine.

Indexed as

AnimalsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsBlood-Brain BarrierBrain NeoplasmsDietary SupplementsDrug CarriersDrug Delivery SystemsGliomaHumansLactoferrinMiceMicellesNanoparticlesNanotechnologyAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsDrug CarriersLactoferrinMicellesAnti-cancerAnti-inflammatoryGliomaLactoferrinMicellesNanoparticles

Identifiers

PMID32707283
PMCPMC7374128
OpenAlexW3045258940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.