ArticleJournal of virological methods2020
Madin-Darby bovine kidney (MDBK) cells are a suitable cell line for the propagation and study of the bovine poxvirus lumpy skin disease virus.
Article in Journal of virological methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 57 citations in OpenAlex.
- Assessment of humoral immune responses elicited by an inactivated lumpy skin disease vaccine in cattle: a preliminary study.The Journal of veterinary medical science · 2026Article
- Persistence of protozoan parasites andApplied and environmental microbiology · 2026Article
- Article
- Lumpy skin disease virus LSDV087 positively regulates innate immune response by promoting oligomerization of MITA/STING.Journal of virology · 2025Article
- Development of high-titer polyclonal antisera targeting a local bovine viral diarrhea virus-1a strain: A preliminary study from Indonesia.Veterinary world · 2025Article
- Molecular detection and phylogenetic analysis of lumpy skin disease virus in Yunnan Province, China from 2019 to 2023.Veterinary research communications · 2025Article
- Article
- Lumpy skin disease virus suppresses the antiviral response of bovine peripheral blood mononuclear cells that support viral dissemination.Veterinary research · 2025Article
- Evaluation of aqueous chlorine and peracetic acid sanitizers to inactivate protozoa and bacteria of concern in agricultural water.Applied and environmental microbiology · 2025Article
- The subunit vaccine of Lumpy skin disease virus elicits significant humoral and cell-mediated immune responses in mice.Frontiers in veterinary science · 2025Article
- Exploring the evolutionary journey of the lumpy skin disease virus through the phylogenetic and phylo-geo network analysis.Frontiers in cellular and infection microbiology · 2025Article
- Sequencing and Analysis of Lumpy Skin Disease Virus Whole Genomes Reveals a New Viral Subgroup in West and Central Africa.Viruses · 2024Article
- Construction of recombinant fluorescent LSDV for high-throughput screening of antiviral drugs.Veterinary research · 2024Article
- Construction of an IFNAR1 knockout MDBK cell line using CRISPR/Cas9 and its effect on bovine virus replication.Frontiers in immunology · 2024Article
- Isolation, adaptation, and characterization of lumpy skin disease virus from cattle in Bangladesh.Journal of advanced veterinary and animal research · 2023Article
- Poxvirus sensitivity of a novel diploid sheep embryonic heart cell line.Archives of virology · 2023Article
- Review
- Effect of bovine viral diarrhea virus biotypes exposure on bovine gametes in early embryonic developmentVeterinary research forum : an international quarterly journal · 2023Article
- Article
- Ruminant-specific retrotransposons shape regulatory evolution of bovine immunity.Genome research · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Lumpy skin disease virus (LSDV) is a poxvirus that causes systemic disease in cattle, resulting in substantial economic loss to affected communities. LSDV is a rapidly emerging pathogen of growing global concern that recently spread from Africa and the Middle East into Europe and Asia, impacting the cattle population in these regions. An increase in research efforts into LSDV is required to address key knowledge gaps, however this is hampered by lack of suitable cell lines on which to propagate and study the virus. In this work we describe the replication and spread of LSDV on Madin-Darby bovine kidney (MDBK) cells, and the formation of foci-type poxvirus plaques by LSDV on MDBK cells. Methods utilising MDBK cells to quantify neutralising antibodies to LSDV, and to purify LSDV genomic DNA suitable for short read sequencing are described. These research methods broaden the tools available for LSDV researchers and will facilitate the gathering of evidence to underpin the development of LSD control and prevention programmes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.