ArticleThe British journal of radiology2020
The implementation of an empty bladder filling protocol for localised prostate volumetric modulated arctherapy (VMAT): early results of a single institution service evaluation.
Article in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- A Reminder App to Optimize Bladder Filling During Radiotherapy for Patients With Prostate Cancer (REFILL-PAC): Protocol for a Prospective Trial.JMIR research protocols · 2025Article
- Patient experience preparing for prostate cancer radiotherapy.Technical innovations & patient support in radiation oncology · 2025Article
- Evaluation of Reminder App for Optimization of Bladder Filling Status During Hypo-Fractionated Irradiation for Prostate Cancer: Protocol of REFILL-PAC-HYPO Trial.Clinics and practice · 2025Article
- Deep learning-based dose prediction for prostate cancer with empty bladder protocol: a framework for efficient and personalized radiotherapy planning.Frontiers in oncology · 2025Article
- A systematic review of prostate bed motion and anisotropic margins in post-prostatectomy external beam radiotherapy.Technical innovations & patient support in radiation oncology · 2024Review
- Prostate stereotactic body radiotherapy: quantifying intra-fraction motion and calculating margins using the new BIR geometric uncertainties in daily online IGRT recommendations.The British journal of radiology · 2023Article
- Maintaining consistent bladder filling during external beam radiotherapy for prostate cancer.Technical innovations & patient support in radiation oncology · 2021Article
- Article
- Frequency and Risk Factors of Inappropriate Bladder Filling in Patients Irradiated for High-risk Prostate Cancer.In vivo (Athens, Greece)Article
- Does Irradiation of Pelvic Lymph Nodes Have an Impact on the Bladder Filling Status in Patients With High-risk Prostate Cancer?In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the impact of an empty bladder filling protocol on patients receiving radical RT for localised prostate cancer on post RT toxicity and biochemical progression free survival (bPFS). METHODS AND MATERIALS: Records of patients receiving radical external beam RT (EBRT) for localised prostate cancer with a full or empty bladder were reviewed. These included the bladder size on planning CT, daily online image guided RT (IGRT) setup data, treatment time and post treatment follow up data.These included bPFS, gastrointestinal(GI) and genitourinary(GU) toxicity scoring post RT using the CTCAE v4.0 scoring system. All patients included in the study were planned and treated under the same departmental clinical protocol with VMAT and daily online IGRT corrections.
results90 patients were treated with 60 Gy in 20 fractions with a median follow up of 48 months. At 4 years bPFS in the empty bladder group was 100 and 98% in the full bladder group (
conclusionAn empty bladder filling protocol has non-inferior bPFS, GI and GU toxicities at 4 years in patients with localised prostate cancer using advanced RT techniques in comparison to a full bladder filling protocol. A longer follow up with a larger sample size is required to validate this approach. ADVANCES IN KNOWLEDGE: This study suggests that an empty bladder filling protocol can be used in external beam EBRT for localised prostate cancer with non-inferior treatment outcomes.
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