ArticleAmerican journal of respiratory and critical care medicine2020
Use of Hydrocortisone, Ascorbic Acid, and Thiamine in Adults with Septic Shock.
Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Therapeutic Role of HAT Therapy in Sepsis: A Systematic Review and Meta-Analysis.Current medicinal chemistry · 2025Pooled it
- Effectiveness of Fludrocortisone Plus Hydrocortisone versus Hydrocortisone Alone in Septic Shock: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.American journal of respiratory and critical care medicine · 2024Pooled it
- Vitamin C in Critically Ill Patients: An Updated Systematic Review and Meta-Analysis.Nutrients · 2021Pooled it
- Unravelling the paradox of vitamin C research in sepsis.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025Review
- Article
- The effects of antioxidant supplementation on short-term mortality in sepsis patients.Heliyon · 2024Article
- Patient Outcomes After Long-Term Acute Care Hospital Closures.JAMA network open · 2023Article
- HAT therapy for sepsis: A review of the therapeutic rationale and current clinical evaluation status.Journal of intensive medicine · 2023Review
- Thiamine for Septic Shock: Take Your Vitamins?American journal of respiratory and critical care medicine · 2023Article
- Decline in Prolonged Acute Mechanical Ventilation, 2011-2019.American journal of respiratory and critical care medicine · 2022Article
- Vitamin C for ≥ 5 days is associated with decreased hospital mortality in sepsis subgroups: a nationwide cohort study.Critical care (London, England) · 2022Article
- Hydrocortisone, ascorbic acid, and thiamine (HAT) for sepsis and septic shock: a meta-analysis with sequential trial analysis.Journal of intensive care · 2021Article
- Review
- Pinpointing the Cause of Variation in Mortality in COVID-19.American journal of respiratory and critical care medicine · 2021Article
- The Efficacy of vitamin C, thiamine, and corticosteroid therapy in adult sepsis patients: a systematic review and meta-analysis.Acute and critical care · 2021Article
- Update in Critical Care 2020.American journal of respiratory and critical care medicine · 2021Review
- Early experience with critically ill patients with COVID-19 in Montreal.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Article
- Evidence and Our Daily Risk Trade-offs in the Care of Critically Ill Patients.American journal of respiratory and critical care medicine · 2020Article
- Early adoption of critical care interventions is unjustifiable without concomitant effectiveness study.Critical care (London, England) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.